Cazzo Everton, Gestic Martinho Antonio, Utrini Murillo Pimentel, Machado Ricardo Rossetto, Pareja José Carlos, Chaim Elinton Adami
Departamento de Cirurgia, Grupo de Cirurgia de Obesidade, Universidade de Campinas ? UNICAMP, Campinas, São Paulo, Brasil.
Arq Gastroenterol. 2014 Jan-Mar;51(1):21-4. doi: 10.1590/s0004-28032014000100005.
Hypertension is a common disorder in general practice and has a widely known association with type 2 diabetes mellitus. Low adhesion to clinical treatment may lead to poor results. Obesity surgery can bring early and relevant resolution rates of both morbidities.
To describe hypertension evolution after Roux-en-Y gastric bypass in patients with type 2 diabetes mellitus.
Descriptive observational study designed as a historical cohort of 90 subjects with hypertension and diabetes who underwent Roux-en-Y gastric bypass and were evaluated before and after surgery.
It was observed a hypertension resolution rate of 85.6% along with markedly decrease in anti-hypertensive usage. Mean resolution time was 3.2 months. Resolution was associated with homeostasis model assessment - insulin resistance, preoperative fasting insulin, anti-hypertensive usage, hypertension time, body mass index and percentage of weight loss. Resolution of hypertension was not statistically associated with diabetes remission within this sample.
Roux-en-Y gastric bypass was a safe and effective therapeutic tool to achieve hypertension resolution in patients who also had diabetes mellitus.
高血压是全科医疗中的常见病症,且与2型糖尿病的关联广为人知。临床治疗依从性低可能导致疗效不佳。肥胖症手术可使这两种病症早期获得显著缓解率。
描述2型糖尿病患者接受Roux-en-Y胃旁路术后高血压的演变情况。
描述性观察性研究,设计为对90例患有高血压和糖尿病且接受了Roux-en-Y胃旁路术的患者进行历史队列研究,并在手术前后进行评估。
观察到高血压缓解率为85.6%,同时抗高血压药物的使用显著减少。平均缓解时间为3.2个月。缓解与稳态模型评估-胰岛素抵抗、术前空腹胰岛素、抗高血压药物使用、高血压病程、体重指数和体重减轻百分比有关。在该样本中,高血压的缓解与糖尿病缓解无统计学关联。
对于同时患有糖尿病的患者,Roux-en-Y胃旁路术是实现高血压缓解的一种安全有效的治疗手段。