Hada M S, Sable M, Kane S V, Pai Prathamesh S, Juvekar S L
Department of Head and Neck Surgical Oncology, Tata Memorial Hospital, Mumbai, Maharashtra, India.
J Cancer Res Ther. 2014 Jan-Mar;10(1):194-6. doi: 10.4103/0973-1482.131411.
The calcifying epithelial odontogenic tumor (CEOT) is a rare benign neoplasm of mandible in adults. The presentation of this entity is varied and often confused with a variety of mucosal and jaw lesions and clinical, radiological, and pathological feature of CEOT often-mimic malignancy. The objective of this report is to highlight the clinical features and radiological findings which should arouse suspicion of a benign lesion and importance of providing adequate clinical information to the pathologist to attain accurate diagnosis.We discussed two cases with tumors located in the maxilla. Both presented as expansile lesions with one biopsy proven squamous cell carcinoma. Both were pursued with clinico-radiological suspicion of benign lesions and confirmed with pathological correlation of histology and immunohistochemistry as CEOT. Therefore a High index of suspicion and clinico-radiological information are the key feature for diagnosis of this rare tumor.
钙化上皮性牙源性肿瘤(CEOT)是成人下颌骨中一种罕见的良性肿瘤。该肿瘤的表现多样,常与多种黏膜和颌骨病变相混淆,其临床、放射学和病理学特征常类似恶性肿瘤。本报告的目的是强调应引起对良性病变怀疑的临床特征和放射学表现,以及向病理学家提供充分临床信息以获得准确诊断的重要性。我们讨论了两例位于上颌骨的肿瘤病例。两例均表现为膨胀性病变,其中一例活检证实为鳞状细胞癌。两例最初均因临床放射学怀疑为良性病变而进行检查,经组织学和免疫组化的病理相关性证实为CEOT。因此,高度的怀疑指数和临床放射学信息是诊断这种罕见肿瘤的关键特征。