Shimazaki Jiro, Motohashi Gyo, Nishida Kiyotaka, Tabuchi Takanobu, Ubukata Hideyuki, Tabuchi Takafumi
Department of Gastrointestinal Surgery, Ibaraki Medical Center, Tokyo Medical University, Ami, Ibaraki 300-0395, Japan.
Oncol Lett. 2014 May;7(5):1464-1468. doi: 10.3892/ol.2014.1913. Epub 2014 Feb 26.
In the current study, a case of recurrent desmoplastic small round cell tumor (DSRCT) is presented, which was successfully treated by repetitive debulking surgery. In May 2010, a 39-year-old male, with a history of surgical resection of intra-abdominal DSRCT, visited the Ibaraki Medical Center, Tokyo Medical University Hospital (Ami, Japan) with severe lower abdominal discomfort. Abdominal computed tomography revealed a large tumor in the pouch of Douglas with a small number of nodules in the abdominal cavity. The recurrent DSRCT was diagnosed and removed via lower anterior resection; however, complete resection was impossible due to multiple peritoneal metastases. One year later, the patient developed pain in the right groin due to the growth of metastasized tumor cells in the groin lymph nodes. The affected lymph nodes were removed utilizing an extra-peritoneal approach. At the time of writing, the patient continues to survive without any symptoms 60 months since the initial surgery. In conclusion, surgical debulking is a significant procedure for relieving patient symptoms as well as improving the survival time of patients with metastatic and recurrent DSRCT.
在本研究中，报告了一例复发性促结缔组织增生性小圆细胞肿瘤（DSRCT），该病例通过重复减瘤手术成功治疗。2010年5月，一名39岁男性，有腹腔DSRCT手术切除史，因严重下腹部不适就诊于东京医科大学附属茨城医疗中心（日本阿见）。腹部计算机断层扫描显示Douglas陷凹有一个大肿瘤，腹腔内有少量结节。复发性DSRCT经诊断后通过下腹部前路切除术切除；然而，由于多处腹膜转移，无法完全切除。一年后，患者因腹股沟淋巴结转移瘤细胞生长出现右腹股沟疼痛。采用腹膜外途径切除受累淋巴结。在撰写本文时，自初次手术以来60个月，患者仍无症状存活。总之，减瘤手术对于缓解患者症状以及提高转移性和复发性DSRCT患者的生存时间是一项重要的手术。
