Ugwumba Fred O, Okafor Okechukwu C, Okoh Agharighom David, Ajuzieogu Obinna Virginus
Urology unit, Department of Surgery;
Department of Morbid Anatomy;
Clin Pract. 2012 Jan 18;2(1):e15. doi: 10.4081/cp.2012.e15. eCollection 2012 Jan 1.
Pheochromocytomas are rare tumors that present a diagnostic challenge in developing countries. They occur in the adrenal gland and as paragangliomas along the sympathetic chain. Clinical features are usually those of sustained or paroxysmal hypertension and complications thereof. Surgical extirpation remains the mainstay of treatment and is greatly facilitated by accurate pre-operative tumor localization. Pre-operative medical management with antihypertensive medication has led to significant reductions in peri-operative mortality. Determination of malignancy is difficult in the absence of obvious metastases. We present a case of left adrenal phechromocytoma that was stabilized. Adrenalectomy had a good outcome and the patient has so far been followed up for a year.
嗜铬细胞瘤是罕见肿瘤,在发展中国家构成诊断挑战。它们发生于肾上腺,也可作为副神经节瘤沿交感神经链出现。临床特征通常为持续性或阵发性高血压及其并发症。手术切除仍是主要治疗方法,准确的术前肿瘤定位极大地促进了手术。术前使用抗高血压药物进行内科治疗已使围手术期死亡率显著降低。在无明显转移的情况下,确定恶性肿瘤很困难。我们报告一例经治疗病情稳定的左肾上腺嗜铬细胞瘤病例。肾上腺切除术效果良好,该患者迄今已随访一年。