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一名20岁尼日利亚人的嗜铬细胞瘤,解决良性或恶性的困境。

Phaeochromocytoma in a 20-year-old Nigerian, resolving the dilemma of benignity or malignancy.

作者信息

Ugwumba Fred O, Okafor Okechukwu C, Okoh Agharighom David, Ajuzieogu Obinna Virginus

机构信息

Urology unit, Department of Surgery;

Department of Morbid Anatomy;

出版信息

Clin Pract. 2012 Jan 18;2(1):e15. doi: 10.4081/cp.2012.e15. eCollection 2012 Jan 1.

DOI:10.4081/cp.2012.e15
PMID:24765414
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3981342/
Abstract

Pheochromocytomas are rare tumors that present a diagnostic challenge in developing countries. They occur in the adrenal gland and as paragangliomas along the sympathetic chain. Clinical features are usually those of sustained or paroxysmal hypertension and complications thereof. Surgical extirpation remains the mainstay of treatment and is greatly facilitated by accurate pre-operative tumor localization. Pre-operative medical management with antihypertensive medication has led to significant reductions in peri-operative mortality. Determination of malignancy is difficult in the absence of obvious metastases. We present a case of left adrenal phechromocytoma that was stabilized. Adrenalectomy had a good outcome and the patient has so far been followed up for a year.

摘要

嗜铬细胞瘤是罕见肿瘤,在发展中国家构成诊断挑战。它们发生于肾上腺,也可作为副神经节瘤沿交感神经链出现。临床特征通常为持续性或阵发性高血压及其并发症。手术切除仍是主要治疗方法,准确的术前肿瘤定位极大地促进了手术。术前使用抗高血压药物进行内科治疗已使围手术期死亡率显著降低。在无明显转移的情况下,确定恶性肿瘤很困难。我们报告一例经治疗病情稳定的左肾上腺嗜铬细胞瘤病例。肾上腺切除术效果良好,该患者迄今已随访一年。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/eac5/3981342/3ed1668426ea/cp-2012-1-e15-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/eac5/3981342/c9d7ea0919c6/cp-2012-1-e15-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/eac5/3981342/04595efc640b/cp-2012-1-e15-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/eac5/3981342/a572d7063d0a/cp-2012-1-e15-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/eac5/3981342/3bc791f6e3f3/cp-2012-1-e15-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/eac5/3981342/3ed1668426ea/cp-2012-1-e15-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/eac5/3981342/c9d7ea0919c6/cp-2012-1-e15-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/eac5/3981342/04595efc640b/cp-2012-1-e15-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/eac5/3981342/a572d7063d0a/cp-2012-1-e15-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/eac5/3981342/3bc791f6e3f3/cp-2012-1-e15-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/eac5/3981342/3ed1668426ea/cp-2012-1-e15-g005.jpg

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本文引用的文献

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Phaeochromocytoma in black South Africans - a 30-year audit.南非黑人嗜铬细胞瘤——30 年回顾性研究。
S Afr Med J. 2011 Mar 1;101(3):184-8. doi: 10.7196/samj.4320.
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Pheochromocytoma: current approaches and future directions.嗜铬细胞瘤:当前方法与未来方向。
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Phaeochromocytoma: current concepts.嗜铬细胞瘤:当前概念
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Pheochromocytoma of the Adrenal gland Scaled Score (PASS) to separate benign from malignant neoplasms: a clinicopathologic and immunophenotypic study of 100 cases.肾上腺嗜铬细胞瘤分级评分(PASS)用于区分良性与恶性肿瘤:100例病例的临床病理及免疫表型研究
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