Wilkinson C
J R Coll Gen Pract. 1988 Oct;38(315):468-9.
Treatment for scabies is usually initiated by general practitioners; most consider lindane (gamma benzene hexachloride) the treatment of choice. Lindane is also widely used as an agricultural and industrial pesticide, and as a result the toxic profile of this insecticide is well understood. Evidence is accumulating that lindane can be toxic to the central nervous system and may be associated with aplastic anaemia. Preparations containing lindane continue to be sold over the counter and may represent a hazard to poorly informed patients. This literature review suggests that general practitioners should prescribe scabicides with increased caution for certain at-risk groups, and give adequate warnings regarding potential toxicity.
疥疮的治疗通常由全科医生开始；大多数人认为林丹（γ-六氯环己烷）是首选治疗药物。林丹还被广泛用作农业和工业杀虫剂，因此这种杀虫剂的毒性特征已为人熟知。越来越多的证据表明，林丹可能对中枢神经系统有毒性，并且可能与再生障碍性贫血有关。含林丹的制剂仍在非处方销售，这可能对了解不足的患者构成危害。这篇文献综述表明，全科医生应更加谨慎地为某些高危人群开疥疮治疗药，并就潜在毒性给予充分警告。
