Sermsathanasawadi Nuttawut, Thangrod Rattana, Hongku Kiattisak, Wongwanit Chumpol, Ruangsetakit Chanean, Chinsakchai Khamin, Leelaphatanadit Chairat, Therasakvichya Suwanit, Mutirangura Pramook
J Med Assoc Thai. 2014 Feb;97(2):153-8.
Thromboprophylaxis of deep vein thrombosis in gynecologic cancer surgery in Thai patients is not routinely performed.
The prevalence of perioperative asymptomatic proximal deep vein thrombosis of 100 patients with gynecologic cancer was identified.
Duplex ultrasonography of proximal vein of legs was performed in each patient, seven to 14 days, before and after surgery.
The prevalence of perioperative asymptomatic proximal deep vein thrombosis was 7%. The prevalence of preoperative asymptomatic proximal deep vein thrombosis of legs was 5% and postoperative incidence of asymptomatic proximal deep vein thrombosis of legs was 2.11%. Acute symptomatic pulmonary embolism was found in only one patient. All patients who developed deep vein thrombosis had adenocarcinoma of ovary or uterus, but not cervical cancer The other risk factors of venous thromboembolism were comparable between deep vein thrombosis and non-deep vein thrombosis group.
The patients with adenocarcinoma of ovary and uterus seem to be the greatest risk of perioperative deep vein thrombosis. High prevalence of venous thromboembolism in gynecologic cancer surgery of Thai patients should be concerned.
泰国患者妇科癌症手术中深静脉血栓形成的预防措施并非常规进行。
确定100例妇科癌症患者围手术期无症状近端深静脉血栓形成的发生率。
对每位患者在手术前后7至14天进行双下肢近端静脉超声检查。
围手术期无症状近端深静脉血栓形成的发生率为7%。术前无症状下肢近端深静脉血栓形成的发生率为5%,术后无症状下肢近端深静脉血栓形成的发生率为2.11%。仅1例患者发生急性症状性肺栓塞。所有发生深静脉血栓形成的患者均患有卵巢癌或子宫腺癌,而非宫颈癌。深静脉血栓形成组与非深静脉血栓形成组之间静脉血栓栓塞的其他危险因素相当。
卵巢癌和子宫腺癌患者似乎是围手术期深静脉血栓形成的最大风险人群。泰国患者妇科癌症手术中静脉血栓栓塞的高发生率应引起关注。