van Rij A M, Chai J, Hill G B, Christie R A
Department of Surgery, Dunedin School of Medicine, University of Otago, PO Box 913, Dunedin, New Zealand.
Br J Surg. 2004 Dec;91(12):1582-5. doi: 10.1002/bjs.4701.
Varicose vein surgery is generally considered to have little risk of postoperative deep vein thrombosis (DVT). This prospective study examined the incidence of DVT in patients undergoing varicose vein surgery.
Lower leg veins were assessed before operation by duplex ultrasonography in 377 patients, and reassessed 2-4 weeks after surgery, and again at 6 and 12 months. Patients were instructed to contact a physician if symptoms consistent with DVT occurred before the scheduled follow-up appointment. Preoperative prophylaxis (a single dose of subcutaneous heparin) was left to the discretion of the vascular surgeon.
DVT was detected in 20 (5.3 per cent) of the 377 patients. Of these, only eight were symptomatic and no patient developed symptoms consistent with pulmonary embolus. Eighteen of the 20 DVTs were confined to the calf veins. Subcutaneous heparin did not alter the outcome. No propagation of thrombus was observed and half of the DVTs had resolved without deep venous reflux at 1 year.
The incidence of DVT following varicose vein surgery was higher than previously thought, but these DVTs had minimal short- or long-term clinical significance.
大隐静脉曲张手术一般被认为术后深静脉血栓形成(DVT)风险较小。本前瞻性研究调查了接受大隐静脉曲张手术患者的DVT发生率。
对377例患者术前采用双功超声评估小腿静脉,术后2 - 4周、6个月和12个月再次评估。若患者在预定随访前出现与DVT相符的症状,需联系医生。术前预防措施(单剂量皮下注射肝素)由血管外科医生自行决定。
377例患者中有20例(5.3%)检测到DVT。其中只有8例有症状,且无患者出现与肺栓塞相符的症状。20例DVT中有18例局限于小腿静脉。皮下注射肝素未改变结果。未观察到血栓蔓延,1年后一半的DVT在无深静脉反流的情况下自行溶解。
大隐静脉曲张手术后DVT的发生率高于此前认为的,但这些DVT的短期或长期临床意义极小。