Angeli Simon I, Telischi Fred F, Eshraghi Adrien A
Department of Otolaryngology, University of Miami Miller School of Medicine, Miami, Florida, USA.
Ann Otol Rhinol Laryngol. 2014 May;123(5):359-64. doi: 10.1177/0003489414526684.
This study aimed to evaluate outcomes of the middle fossa (MF) superior vestibular neurectomy in unilateral Ménière's disease.
Case series with preoperative and postoperative analysis of the 1995 American Academy of Otolaryngology hearing stage and vertigo class, gait instability, and results of vestibular-evoked myogenic potentials (VEMP).
Four out of the 5 patients had total vertigo control (class A) and 1 had near total control (class B) by the last visit (mean follow-up, 23.6 months). There were no changes in hearing thresholds and hearing stage. Four patients had resolution of their gait instability by 2 months after surgery. Postoperative VEMP responses were preserved in all 3 patients with positive VEMP preoperatively.
This is the first report of the anatomical and functional preservation of the inferior vestibular nerve in vestibular neurectomy for the treatment of refractory vertigo in unilateral Ménière's disease, with VEMP testing before and after vestibular neurectomy. The modified technique limits the surgical dissection and may help avoid complications such as postoperative hearing loss and persistent gait instability. This approach is indicated when other more conservative measures have failed, and patient selection is paramount to avoid long-term complications.
本研究旨在评估中颅窝(MF)上前庭神经切除术治疗单侧梅尼埃病的效果。
对1995年美国耳鼻咽喉头颈外科学会听力分级和眩晕分级、步态不稳情况以及前庭诱发肌源性电位(VEMP)结果进行术前和术后分析的病例系列研究。
5例患者中,4例在末次随访时眩晕完全得到控制(A级),1例接近完全控制(B级)(平均随访23.6个月)。听力阈值和听力分级无变化。4例患者术后2个月步态不稳症状消失。术前VEMP阳性的3例患者术后VEMP反应均得以保留。
这是首篇关于在前庭神经切除术中保留前庭下神经的解剖结构和功能以治疗单侧梅尼埃病难治性眩晕,并在前庭神经切除术前和术后进行VEMP检测的报告。改良技术限制了手术剥离范围,可能有助于避免术后听力损失和持续性步态不稳等并发症。当其他更保守的措施无效时可采用此方法,而患者的选择对于避免长期并发症至关重要。