Baryshnikov A Iu, Zabotina T N, Dubinkin I V, Korotkova O V, Shchvartsbergs A M
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Monoclonal antibodies (MoAB) ICO-45 discovered the antigen with 45 kD molecular mass, expressed on the surface of 77% thymocytes, 68% monocytes, 95% granulocytes, 46% T-lymphocytes, 59% non-T-lymphocytes. MoAB ICO-45 blocked T-lymphocyte blast transformation and inhibited the respiratory burst of monocytes and granulocytes of the peripheral blood.
单克隆抗体ICO - 45发现了分子量为45 kD的抗原,该抗原在77%的胸腺细胞、68%的单核细胞、95%的粒细胞、46%的T淋巴细胞、59%的非T淋巴细胞表面表达。单克隆抗体ICO - 45阻断T淋巴细胞的母细胞转化,并抑制外周血单核细胞和粒细胞的呼吸爆发。