Yamada Hirofumi, Yamamoto Akira, Okada Tomohisa, Kanagaki Mitsunori, Fushimi Yasutaka, Mehemed Taha Mohamed, Porter David A, Togashi Kaori
Department of Diagnostic Imaging and Nuclear Medicine, Kyoto University Graduate School of Medicine, 54 Shogoin-Kawaharacho, Sakyo-ku, Kyoto, 606-8507, Japan.
Surg Radiol Anat. 2014 Dec;36(10):973-80. doi: 10.1007/s00276-014-1299-1. Epub 2014 Apr 26.
To investigate the diffusion tensor imaging parameters of the optic radiation and surrounding structures using the high-resolution readout-segmented diffusion tensor imaging method.
Coronal readout-segmented diffusion tensor images were acquired in 15 healthy volunteers. On three slices of each image, eigenvalue 1, fractional anisotropy, radial diffusivity, apparent diffusion coefficient, and signal intensity on T2-weighted images were measured in the lateral inferior longitudinal fasciculus, external and internal layers of the optic radiation, and the tapetum within regions of interest delineated by two independent observers. Profile curve analysis of regions of interest across the optic radiation and surrounding structures was performed for a representative typical case.
Significant differences in fractional anisotropy, radial diffusivity and apparent diffusion coefficient were observed between external and internal layers of the optic radiation, while there was no significant difference in eigenvalue 1. In fractional anisotropy maps, two low signal bands were observed between the inferior longitudinal fasciculus, the optic radiation and the tapetum. Profile curve analysis showed a minimum on the fractional anisotropy and eigenvalue 1 images and a maximum in the radial diffusivity image.
Readout-segmented diffusion tensor imaging revealed significant differences in the diffusion tensor imaging parameters between internal and external layers of the optic radiation.
采用高分辨率读出分段扩散张量成像方法研究视辐射及周围结构的扩散张量成像参数。
对15名健康志愿者采集冠状位读出分段扩散张量图像。在每个图像的三个层面上，由两名独立观察者在划定的感兴趣区域内，测量下外侧纵束、视辐射的外层和内层以及脉络膜毯的特征值1、分数各向异性、径向扩散率、表观扩散系数和T2加权图像上的信号强度。对一个具有代表性的典型病例进行了视辐射及周围结构感兴趣区域的轮廓曲线分析。
视辐射的外层和内层之间在分数各向异性、径向扩散率和表观扩散系数方面存在显著差异，而特征值1无显著差异。在分数各向异性图中，在下外侧纵束、视辐射和脉络膜毯之间观察到两个低信号带。轮廓曲线分析显示分数各向异性和特征值1图像上有最小值，径向扩散率图像上有最大值。
读出分段扩散张量成像显示视辐射的内层和外层之间在扩散张量成像参数上存在显著差异。
