Department Pathology, Armed Police Corps Hospital of Chongqing, Chongqing 400061, China.
Diagn Pathol. 2014 Apr 28;9:87. doi: 10.1186/1746-1596-9-87.
Cystadenocarcinoma is primarily characterized by cystic structures of varying sizes, that are lined by epithelial cells. As a rare neoplasm, only four cases of cystadenocarcinoma of submandibular glands have been previously reported. Herein, we reported a unique case of submandibular gland cystadenocarcinoma in a 44-year-old man. By in large, this case had typical morphologic cystadenocarcinoma features. However, mucinous adenocarcinoma-like areas were additionally observed in the tumor tissues. This case was initially misdiagnosed as mucinous adenocarcinoma due to the low incidence of submandibular gland cystadenocarcinoma and the presentation of mucinous adenocarcinoma-like areas in the tumor tissues. Histopathology of additional tumor tissues revealed that mucinous adenocarcinoma-like areas accounted for only a small percentage of the tumor tissues, confirming the submandibular gland cystadenocarcinoma diagnosis.
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囊腺癌的主要特征是大小不一的囊状结构，由上皮细胞排列而成。作为一种罕见的肿瘤，以前仅报道过 4 例下颌下腺囊腺癌。在此，我们报告了 1 例 44 岁男性下颌下腺囊腺癌的独特病例。大体上，该病例具有典型的囊腺癌形态特征。然而，肿瘤组织中还观察到黏液性腺癌样区域。由于下颌下腺囊腺癌发病率低，且肿瘤组织中存在黏液性腺癌样区域，该病例最初被误诊为黏液性腺癌。对额外肿瘤组织的组织病理学检查显示，黏液性腺癌样区域仅占肿瘤组织的一小部分，从而证实了下颌下腺囊腺癌的诊断。
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