Ruwanpathirana T, Fernando D N
Family Health Bureau, Ministry of Health, Colombo, Sri Lanka,
Indian J Pediatr. 2014 Oct;81(10):1000-4. doi: 10.1007/s12098-014-1382-y. Epub 2014 Apr 30.
To identify the risk factors for small for gestational age (SGA) babies.
The present study was a nested case control study which was carried out by two Medical Officers of Health areas (The field level administrative unit responsible for provision of preventive and promotive health services) in Colombo district. SGA babies were identified using 'weight for gestational age' curves developed for Sri Lankan babies. Newborns of 1,200 pregnant women, who were identified within the first 8 wk of amenorrhea and who delivered in selected hospitals were included in the study. Sample size was calculated as n=167 cases and 4 n=668 controls, with four controls for each case. A case was defined as a newborn whose birth weight was less than the 10th percentile of the weight for gestational age, the control being a newborn whose birth weight was between the 10th and the 90th percentile of the weight for gestational age.
Multivariate analysis identified 7 significant risk factors as, number of live born children=0, inadequate weight gain during pregnancy according to initial BMI, maximum and minimum physical work, mother's pre-pregnant weight less than 38 kg, high level of stress at second trimester, presence of pregnancy induced hypertension (PIH) and inadequate support from husband.
The risk factors indicate the directions for planning intervention programs.
确定小于胎龄儿(SGA)的危险因素。
本研究为巢式病例对照研究,由科伦坡地区两个卫生区的两名卫生官员(负责提供预防和促进健康服务的基层行政单位)开展。使用为斯里兰卡婴儿制定的“胎龄体重”曲线来确定小于胎龄儿。研究纳入了1200名孕妇的新生儿,这些孕妇在闭经的前8周内被识别出来,并在选定的医院分娩。样本量计算为n = 167例病例和4n = 668例对照,即每个病例有4个对照。病例定义为出生体重低于胎龄体重第10百分位数的新生儿,对照为出生体重在胎龄体重第10至第90百分位数之间的新生儿。
多变量分析确定了7个显著危险因素,即活产子女数=0、根据初始体重指数孕期体重增加不足、最大和最小体力活动、孕前体重小于38 kg、孕中期压力水平高、妊娠高血压(PIH)以及丈夫支持不足。
这些危险因素为规划干预项目指明了方向。