Yin Zhaoxue, Shi Xiaoming, Kraus Virginia B, Brasher Melanie Sereny, Chen Huashuai, Liu Yuzhi, Lv Yuebin, Zeng Yi
Division of Non-communicable Diseases Control and Community Health, Chinese Center for Disease Control and Prevention, Beijing, China.
Department of Medicine, Duke University School of Medicine, Durham, NC, USA.
Obesity (Silver Spring). 2014 Aug;22(8):1918-1925. doi: 10.1002/oby.20775. Epub 2014 Apr 29.
To explore associations of BMI and waist circumference (WC) with disability among the Chinese oldest old.
The 5,495 oldest old in the sixth wave of Chinese Longitudinal Healthy Longevity Study conducted in 2011 were included in this study. Disability was assessed by activities of daily living (ADL); height and weight for BMI and WC were measured; information including socio-demographics, lifestyles, and health status was collected.
Generalized additive models analysis showed that the association of BMI/WC with ADL disability was nonlinear. Among the males, logistic regression results supported a "J" shape association between ADL disability with BMI/WC-the highest tertile group in BMI or WC was significantly associated with an increased risk of ADL disability: odds ratio 1.78 (95% confidence interval (CI): 1.26-2.52) for BMI and 2.01 (95% CI: 1.44-2.82) for WC. Among females, an inverse "J" shape association was found, only the lowest tertile group before the cutoff point had an increased risk of ADL disability: odds ratio 1.42 (95%CI: 1.02-1.97) for BMI and 1.47 (95% CI:1.06-2.04) for WC.
Associations of BMI and WC with ADL disability are significant even in the oldest old, but differ between the genders.
探讨中国高龄老人中体重指数(BMI)和腰围(WC)与残疾之间的关联。
本研究纳入了2011年进行的中国老年健康长寿纵向研究第六波中的5495名高龄老人。通过日常生活活动(ADL)评估残疾情况;测量身高和体重以计算BMI和WC;收集包括社会人口统计学、生活方式和健康状况等信息。
广义相加模型分析显示,BMI/WC与ADL残疾之间的关联是非线性的。在男性中,逻辑回归结果支持ADL残疾与BMI/WC之间呈“J”形关联——BMI或WC最高三分位数组与ADL残疾风险增加显著相关:BMI的比值比为1.78(95%置信区间(CI):1.26 - 2.52),WC的比值比为2.01(95%CI:1.44 - 2.82)。在女性中,发现呈倒“J”形关联,仅截止点前最低三分位数组有ADL残疾风险增加:BMI的比值比为1.42(95%CI:1.02 - 1.97),WC的比值比为1.47(95%CI:1.06 - 2.04)。
即使在高龄老人中,BMI和WC与ADL残疾之间的关联也很显著,但存在性别差异。