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[乙醇对糖尿病发病类型的影响]

[Influence of ethyl alcohol on diabetes pathogenesis type].

作者信息

Zasimowicz Elzbieta, Wolszczak Blanka, Zasimowicz Barbara

出版信息

Pol Merkur Lekarski. 2014 Mar;36(213):212-4.

Abstract

Relations between metabolism of carbohydrates and ethyl alcohol consumption became a subject of many research because they occur very frequently amongst alcoholics. One of the most often and dangerous effects of abusing ethanol is hypoglycemia. It is caused by hepatic gluconeogenesis disturbed by ethyl alcohol. Chronic result of abusing alcohol is chronic pancreas inflammation (PZT), what causes disorders of exo- and endocrine function of pancreas. Endocrine function is secretion of insulin and the glucagon what regulates metabolism of absorbed compounds. Failure of beta cells of Langerhans islets causes diabetes demanding insulin therapy. The ethanol can cause recurring diabetes resulting from damage of cells of Langerhans islets but can be also the risk factor of diabetes type 2.

摘要

碳水化合物代谢与乙醇摄入之间的关系成为众多研究的课题,因为它们在酗酒者中非常常见。滥用乙醇最常见且危险的影响之一是低血糖。它是由乙醇干扰肝脏糖异生引起的。滥用酒精的慢性后果是慢性胰腺炎(PZT),这会导致胰腺外分泌和内分泌功能紊乱。内分泌功能是胰岛素和胰高血糖素的分泌,它们调节吸收化合物的代谢。朗格汉斯胰岛β细胞功能衰竭会导致需要胰岛素治疗的糖尿病。乙醇会因朗格汉斯胰岛细胞受损导致复发性糖尿病,但也可能是2型糖尿病的危险因素。

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