Szalaty H, Jankowska R, Małolepszy J, Sypuła A, Zielińska-Jenczylik J
Department of Immunology of Infectious Diseases, Institute of Immunology and Experimental Therapy, Wrocław.
Arch Immunol Ther Exp (Warsz). 1988;36(5):517-21.
Investigations were carried out on 28 patients with nonatopic bronchial asthma treated with glycocorticosteroids or antibiotics and on 15 patients with atopic bronchial asthma treated with Alavac S vaccine. Leukocytes isolated from these patients by the method of Mogensen and Cantell were induced with Newcastle disease virus for interferon production, IFN was tested in the culture of human fibroblasts (HAT). The production of leukocytic IFN in glycocorticosteroids- and antibiotics-treated patients was shown to increase. On the contrary, the leukocytes from the patients 3 months treated with Alavac S exhibited suppressed production of the interferon.
对28例接受糖皮质激素或抗生素治疗的非特应性支气管哮喘患者以及15例接受阿拉瓦克S疫苗治疗的特应性支气管哮喘患者进行了研究。通过莫根森和坎特尔方法从这些患者中分离出的白细胞用新城疫病毒诱导产生干扰素，干扰素在人成纤维细胞（HAT）培养物中进行检测。结果显示，接受糖皮质激素和抗生素治疗的患者白细胞干扰素产量增加。相反，接受阿拉瓦克S治疗3个月的患者白细胞干扰素产量受到抑制。
