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36例甲状腺功能亢进症合并特发性血小板减少性紫癜临床分析

[Clinical analysis of 36 cases of coexistent hyperthyroidism with idiopathic thrombocytopenic purpura].

作者信息

Ma M X, Yu J R, Cai Z Q

出版信息

Zhonghua Nei Ke Za Zhi. 1989 Mar;28(3):136-8, 185.

PMID:2478342
Abstract

36 cases of coexistent hyperthyroidism and idiopathic thrombocytopenic purpura (ITP) were reported. There were 33 cases of overt hyperthyroidism with ITP. After treatment with antithyroid drugs the platelet count returned to normal in 29 and somewhat increased in the remaining four cases. The other three cases had ITP accompanied by hyperthyroidism. In 2 cases the platelet count decreased when they had accompanying hyperthyroidism. When the thyroid function returned to normal after antithyroid treatment, the platelet count returned to normal in one and increased in another. The authors discussed the association between hyperthyroidism and ITP and treatment of coexistent hyperthyroidism and ITP. Probable mechanisms causing thrombocytopenia in hyperthyroidism were discussed also.

摘要

报告了36例合并甲状腺功能亢进症和特发性血小板减少性紫癜(ITP)的病例。其中33例为显性甲状腺功能亢进症合并ITP。使用抗甲状腺药物治疗后,29例患者的血小板计数恢复正常,其余4例有所升高。另外3例为ITP合并甲状腺功能亢进症。其中2例在合并甲状腺功能亢进症时血小板计数下降。抗甲状腺治疗后甲状腺功能恢复正常时,1例患者的血小板计数恢复正常,另1例升高。作者讨论了甲状腺功能亢进症与ITP之间的关联以及合并甲状腺功能亢进症和ITP的治疗方法。还讨论了甲状腺功能亢进症导致血小板减少的可能机制。

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