眼球运动作为精神分裂症中伴随放电功能的一种探测手段。
Eye movements as a probe of corollary discharge function in schizophrenia.
作者信息
Pack Christopher C
机构信息
McGill University , Montreal, Quebec, Canada H3A 2B4.
出版信息
ACS Chem Neurosci. 2014 May 21;5(5):326-8. doi: 10.1021/cn5000869. Epub 2014 May 1.
Abstract
Nearly every movement made by every animal is accompanied by a corollary discharge, a signal sent from the motor to sensory regions of its brain. Corollary discharges are a crucial mechanism by which the brain monitors its own actions, and there is some evidence that they are impaired in people with schizophrenia. Here, I briefly review this evidence and suggest that eye movements are a particularly valuable tool for assessing the role of corollary discharges in schizophrenia.
摘要
几乎每种动物的每一个动作都伴随着一个伴随放电，即从其大脑的运动区域发送到感觉区域的信号。伴随放电是大脑监测自身动作的关键机制，并且有一些证据表明，精神分裂症患者的这种机制受损。在此，我简要回顾一下这一证据，并指出眼球运动是评估伴随放电在精神分裂症中作用的一个特别有价值的工具。
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