Ushenko A G, Angelsky P O, Sidor M, Marchuk Yu F, Andreychuk D R, Pashkovskaya N V
Appl Opt. 2014 Apr 1;53(10):B172-80. doi: 10.1364/AO.53.00B172.
The theoretical background of correlation and phase analysis of laser images of human blood plasma with the spatial-frequency selection of the manifestations of mechanisms of linear and circular birefringence of albumin and globulin is presented. The comparative results of measuring the coordinate distributions of the module of complex degree of coherence (CDC) of laser images of blood plasma taken from the patients of three groups--healthy patients (donors), the patients suffering from the rheumatoid arthritis, and those with stomach cancer (adenocarcinoma)--are shown. The values and ranges of change of the statistical (moments of the first-fourth orders), correlation (excess of autocorrelation functions), and fractal (slopes of approximating curves and dispersion of the extremes of logarithmic dependencies of power spectra) parameters of CDC coordinate distributions are studied. The objective criteria of diagnostics of the pathology and differentiation of the inflammation and oncological state are determined.
本文介绍了人体血浆激光图像相关性和相位分析的理论背景,该分析涉及白蛋白和球蛋白线性及圆双折射机制表现的空间频率选择。展示了从三组患者——健康患者(供血者)、类风湿性关节炎患者和胃癌(腺癌)患者——采集的血浆激光图像复相干度(CDC)模的坐标分布测量的对比结果。研究了CDC坐标分布的统计参数(一阶至四阶矩)、相关参数(自相关函数的超量)和分形参数(近似曲线的斜率以及功率谱对数依赖性极值的离散度)的值及变化范围。确定了疾病诊断以及炎症和肿瘤状态鉴别的客观标准。