癌症疼痛与当前的疼痛控制理论

Cancer pain and current theory for pain control.

作者信息

Kahan Brian

机构信息

The Kahan Center for Pain Management, 2002 Medical Parkway, Suite 150, Annapolis, MD 21401, USA.

出版信息

Phys Med Rehabil Clin N Am. 2014 May;25(2):439-56. doi: 10.1016/j.pmr.2014.01.013.

DOI:10.1016/j.pmr.2014.01.013

PMID:24787342

Abstract

This article discusses current trends in managing cancer pain, with specific regard to opioid transmission, descending pathway inhabitation, and ways to facilitate the endogenous antinociceptive chemicals in the human body. Various techniques for opioid and nonopioid control of potential pain situations of patients with cancer are discussed. The benefits of using pharmacogenetics to assess the appropriate medications are addressed. Finally, specific treatment of abdominal cancer pain using radiofrequency lesioning is discussed.

摘要

本文讨论了癌症疼痛管理的当前趋势，特别涉及阿片类药物传递、下行通路抑制以及促进人体内源性抗痛觉化学物质的方法。文中讨论了对癌症患者潜在疼痛情况进行阿片类和非阿片类控制的各种技术。还阐述了利用药物遗传学评估合适药物的益处。最后，讨论了使用射频消融术治疗腹部癌症疼痛的具体方法。