Grimbert P, Lebreton O, Weber M
Service d'ophtalmologie, centre hospitalier du Mans, 194, avenue Rubillard, 72000 Le Mans, France.
Service d'ophtalmologie, CHU de Nantes, 1, place Alexis-Ricordeau, 44093 Nantes cedex 1, France.
J Fr Ophtalmol. 2014 Jun;37(6):434-41. doi: 10.1016/j.jfo.2014.02.005. Epub 2014 May 1.
To evaluate the anatomical and functional consequences of internal limiting membrane (ILM) peeling in epiretinal membrane (ERM) surgery.
Retrospective single-center study including consecutive patients operated on for idiopathic ERM. The integrity of the ILM was assessed by ILM Blue® staining after removal of the ERM: either the peeling was spontaneous (group 1) or a complementary peeling was required (group 2). Pre- and post-operatively (1 and 6 months), all patients were analyzed using visual acuity, SD-OCT (Spectralis HRA OCT, Heidelberg, Germany) and microperimetry (OPKO/OTI, Miami, USA).
Twenty-one eyes of 21 patients were included: 12 "active ILM peelings" and 9 "spontaneous peelings". In both groups, visual acuity increased significantly after surgery. Microperimetry revealed more microscotomata at 1 and 6 months for active peeling (P<0.05). Their location corresponded more often to the site where the ERM or ILM was grasped, based on surgical videos (P<0.05), and with the appearance of inner retinal defects using en face OCT.
ILM peeling is frequently performed to reduce ERM recurrence. Despite lack of effect on visual acuity, active ILM peeling increases the incidence of microscotomas related to the site where the ERM or ILM is grasped.
Active ILM peeling may be responsible for postoperative visual discomfort related to microscopic trauma during peeling.
评估视网膜前膜(ERM)手术中内界膜(ILM)剥除的解剖学和功能后果。
一项回顾性单中心研究,纳入连续接受特发性ERM手术的患者。在剥除ERM后,通过ILM Blue®染色评估ILM的完整性:剥除为自发性(第1组)或需要辅助剥除(第2组)。术前及术后(1个月和6个月),使用视力、SD-OCT(德国海德堡Spectralis HRA OCT)和微视野计(美国迈阿密OPKO/OTI)对所有患者进行分析。
纳入21例患者的21只眼:12例“主动ILM剥除”和9例“自发性剥除”。两组患者术后视力均显著提高。微视野计显示,主动剥除组在术后1个月和6个月出现更多微视野缺损(P<0.05)。根据手术视频,这些缺损的位置更常对应于ERM或ILM被抓取的部位(P<0.05),并且在正面OCT上出现视网膜内层缺损。
经常进行ILM剥除以降低ERM复发率。尽管对视力无影响,但主动ILM剥除增加了与ERM或ILM被抓取部位相关的微视野缺损发生率。
主动ILM剥除可能是导致剥除过程中微观创伤引起术后视觉不适的原因。