Castañeda F, Isorna S, Hulbert J C, Repa I, Maynar-Moliner M, Hunter D W, Castañeda-Zuñiga W R, Amplatz K
Department of Radiology, University of Minnesota Hospital and Clinic, Minneapolis 55455.
AJR Am J Roentgenol. 1989 Dec;153(6):1301-4. doi: 10.2214/ajr.153.6.1301.
We performed balloon urethroplasty in six older normal dogs and 10 patients with benign prostatic hypertrophy to establish the mechanism by which this technique results in relief of bladder outlet obstruction. Thirty-millimeter balloon catheters were used in both the animal and human studies. Autopsy studies showed disruption of the anterior prostatic commissure in four of the six dogs, disruption of both anterior and posterior commissures in one dog, and no disruption in the remaining dog. In all 10 patients, cystoscopy and urethrography showed disruption of the anterior commissure. Separation of the prostatic lobes by disruption of the prostatic commissures may be the most important mechanism by which balloon urethroplasty relieves urethral obstruction.
我们对6只老年正常犬和10例良性前列腺增生患者进行了球囊尿道成形术，以确定该技术缓解膀胱出口梗阻的机制。在动物和人体研究中均使用了30毫米的球囊导管。尸检研究显示，6只犬中有4只前列腺前联合中断，1只犬前后联合均中断，其余1只犬未中断。在所有10例患者中，膀胱镜检查和尿道造影显示前联合中断。通过破坏前列腺联合来分离前列腺叶可能是球囊尿道成形术缓解尿道梗阻的最重要机制。
