Juji F, Takashima H, Takaishi T, Morita Y, Ito K, Miyamoto T
Department of Pediatrics, Faculty of Medicine, University of Tokyo, Japan.
Ann Allergy. 1989 Nov;63(5):427-33.
Fifty-eight mite-allergic asthmatic patients ages 15 to 22 years were examined. Low respiratory threshold to acetyl-choline (RT-Ach), high maximal histamine release (HR) by mite and anti-IgE, high serum IgE levels and high eosinophil counts were highly associated with the severity of asthma. RT-Ach correlated inversely with HR to mite and anti-IgE. The maximal histamine release from leukocyte caused by anti-IgE also correlated highly with the severity of asthma.
对58名年龄在15至22岁之间的螨过敏哮喘患者进行了检查。对乙酰胆碱的低呼吸阈值(RT-Ach)、螨和抗IgE引起的高组胺最大释放量(HR)、高血清IgE水平和高嗜酸性粒细胞计数与哮喘严重程度高度相关。RT-Ach与螨和抗IgE的HR呈负相关。抗IgE引起的白细胞组胺最大释放量也与哮喘严重程度高度相关。