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青少年及青年哮喘的临床研究。实验室检查结果与哮喘严重程度之间的相关性。

Clinical study of asthma in adolescents and in young adults. Correlation between laboratory findings and severity of asthma.

作者信息

Juji F, Takashima H, Takaishi T, Morita Y, Ito K, Miyamoto T

机构信息

Department of Pediatrics, Faculty of Medicine, University of Tokyo, Japan.

出版信息

Ann Allergy. 1989 Nov;63(5):427-33.

PMID:2479302
Abstract

Fifty-eight mite-allergic asthmatic patients ages 15 to 22 years were examined. Low respiratory threshold to acetyl-choline (RT-Ach), high maximal histamine release (HR) by mite and anti-IgE, high serum IgE levels and high eosinophil counts were highly associated with the severity of asthma. RT-Ach correlated inversely with HR to mite and anti-IgE. The maximal histamine release from leukocyte caused by anti-IgE also correlated highly with the severity of asthma.

摘要

对58名年龄在15至22岁之间的螨过敏哮喘患者进行了检查。对乙酰胆碱的低呼吸阈值(RT-Ach)、螨和抗IgE引起的高组胺最大释放量(HR)、高血清IgE水平和高嗜酸性粒细胞计数与哮喘严重程度高度相关。RT-Ach与螨和抗IgE的HR呈负相关。抗IgE引起的白细胞组胺最大释放量也与哮喘严重程度高度相关。

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Ann Allergy. 1989 Nov;63(5):427-33.
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