Singh David K, Viswanathan Mohan N, Tanel Ronn E, Lee Randall J, Lee Byron K, Marcus Gregory M, Olgin Jeffrey E, Han Frederick, Vedantham Vasanth, Tseng Zian H, Pellegrini Cara, Kawamura Mitsuharu, Gerstenfeld Edward P, Badhwar Nitish, Scheinman Melvin
Division of Cardiology, Queens Medical Center, Honolulu, Hawaii.
Division of Cardiology, University of Washington, Seattle, Washington.
Heart Rhythm. 2014 Aug;11(8):1327-35. doi: 10.1016/j.hrthm.2014.04.038. Epub 2014 May 2.
Because the His bundle is intrinsic to the circuit in orthodromic reciprocating tachycardia and remote from that of atrioventricular nodal reentrant tachycardia (AVNRT), pacing the His bundle during supraventricular tachycardia (SVT) may be useful to distinguish these arrhythmias.
The purpose of this study was to test the hypothesis that His overdrive pacing (HOP) would affect SVT immediately for orthodromic reciprocating tachycardia and in a delayed manner for AVNRT.
Once SVT was induced, HOP was performed by pacing the His bundle 10-30 ms faster than the SVT cycle length. The maneuver was determined to have entered the tachycardia circuit when a nonfused His-capture beat advanced or delayed the subsequent atrial electrogram by ≥10 ms or when the tachycardia was terminated. The number of beats required to enter each tachycardia with HOP was recorded.
HOP was performed during 66 SVTs (26 atrioventricular reciprocating tachycardia [AVRT] and 40 AVNRT). Entry into the tachycardia within 1 beat had sensitivity of 92%, specificity of 92%, positive predictive value (PPV) of 89% and negative predictive value (NPV) of 95% to confirm the diagnosis of AVRT. A cutoff ≥3 beats to enter the circuit had sensitivity of 90%, specificity of 92%, PPV of 95% and NPV of 86% to confirm the diagnosis of AVNRT. HOP had sensitivity, specificity, PPV, and NPV of 100% for distinguishing septal AVRT from atypical AVNRT.
HOP during SVT is a novel technique for distinguishing orthodromic reciprocating tachycardia from AVNRT. It can reliably distinguish between these arrhythmias with high sensitivity and specificity.
由于希氏束在顺向性折返性心动过速的折返环路中,而远离房室结折返性心动过速(AVNRT)的折返环路,因此在室上性心动过速(SVT)期间对希氏束进行起搏可能有助于鉴别这些心律失常。
本研究旨在验证以下假设,即希氏束超速起搏(HOP)对顺向性折返性心动过速的室上性心动过速会立即产生影响,而对房室结折返性心动过速则产生延迟影响。
一旦诱发室上性心动过速,通过以比室上性心动过速周期长度快10 - 30毫秒的频率对希氏束进行起搏来实施希氏束超速起搏。当一个非融合的希氏束夺获搏动使随后的心房电图提前或延迟≥10毫秒,或者当心动过速终止时,判定该操作已进入心动过速环路。记录通过希氏束超速起搏进入每种心动过速所需的搏动次数。
在66次室上性心动过速期间进行了希氏束超速起搏(26次房室折返性心动过速[AVRT]和40次房室结折返性心动过速)。1次搏动内进入心动过速对确诊房室折返性心动过速的敏感性为92%,特异性为92%,阳性预测值(PPV)为89%,阴性预测值(NPV)为95%。进入环路的搏动数≥3次对确诊房室结折返性心动过速的敏感性为90%,特异性为92%,PPV为95%,NPV为86%。希氏束超速起搏在鉴别间隔旁道房室折返性心动过速与不典型房室结折返性心动过速方面的敏感性、特异性、PPV和NPV均为100%。
室上性心动过速期间的希氏束超速起搏是一种鉴别顺向性折返性心动过速与房室结折返性心动过速的新技术。它能够以高敏感性和特异性可靠地鉴别这些心律失常。