Ma Chao-Yang, Huang Qi, Wan Wen-Jun, Zhou Li, Tang Lei, Wang Yan Fu, Luo Qin-Qin, Zhang Ting, Wang Ying
Zhongguo Zhen Jiu. 2014 Feb;34(2):125-9.
To observe effects of syndrome-differentiation acupuncture on life quality in patients with functional dyspepsia (FD) in order to evaluate its clinical efficacy.
One hundred and five cases of FD were randomly divided into a syndrome-differentiation acupuncture group, a regular acupuncture group and a non-acupoint group, 35 cases in each one. Zhongwan (CV 12), Tianshu (ST 25), Zusanli (ST 36) were selected as main acupoints in the syndrome-differentiation acupuncture group. After syndrome differentiation, Danzhong (CV 17) and Zhangmen (LR 13) were added for those with stagnation of liver qi; Pishu (BL 20) and Weishu (BL 21) were added for those with deficiency of spleen-stomach qi; Qimen (LR 14) and Taichong (LR 3) were added for liver-qi invading stomach and Yinlingquan (SP 9) and Neiting (ST 44) were added for dampness-heat blocking stomach. The selection of acupoints in the regular acupuncture group was the same as main acupoints in the syndrome-differentiation acupuncture group. The points 10 mm lateral to the main acupoints were selected in the non-acupoint group. The treatment was given once a day, six days as a treatment course and totally two courses were required. The symptom total score, health-related quality of life survey (SF-36) and Nepean dyspepsia index (NDI) were evaluated before and after the treatment as well as one month after the treatment (follow-up visit), respectively. The efficacy was also assessed.
After the treatment, the total effective rate was 87.5% (28/32) in the syndrome-differentiation acupuncture group, which was superior to 74.2% (23/31) in the regular acupuncture group and 20.7% (6/29) in the non-acupoint group (P < 0.05, P < 0.01). Compared before the treatment, the SF-36, NDI and symptom total score after the treatment and in the follow-up visit were all obviously improved in the syndrome-differentiation acupuncture group and regular acupuncture group (all P < 0.05), which was the most obvious in the syndrome-differentiation acupuncture group [after the treatment, SF-36: 84.54 +/- 5.93 vs 81.44 +/- 6.22, 63.46 +/- 6.59; NDSI: 18.94 +/- 9.30 vs 21.23 +/- 8.39, 43.93 +/- 11.26; NDLQI: 71.42 +/- 7.23 vs 63.11 +/- 7.06, 54.87 +/- 6.00; symptom total score: 22.06 +/- 15.80 vs 32.52 +/- 16.88, 47.97 +/- 10.92]; the improvement in the regular acupuncture group was more obvious than that in the non-acupoint group (P < 0.01, P < 0.05). Compared before the treatment, only NDSI score was improved in the non-acupoint group after the treatment (P < 0.05).
The syndrome-differentiation acupuncture could obviously improve patient's life quality in the treatment of FD, which is an effective therapy for FD.
观察辨证施针治疗功能性消化不良（FD）患者对其生活质量的影响，以评估其临床疗效。
将105例FD患者随机分为辨证施针组、常规针刺组和非穴位组，每组35例。辨证施针组选取中脘（CV12）、天枢（ST25）、足三里（ST36）作为主穴。辨证后，肝气郁结者加膻中（CV17）、章门（LR13）；脾胃气虚者加脾俞（BL20）、胃俞（BL21）；肝胃不和者加期门（LR14）、太冲（LR3）；湿热阻胃者加阴陵泉（SP9）、内庭（ST44）。常规针刺组选取穴位与辨证施针组主穴相同。非穴位组选取主穴旁开10mm处的点。治疗每日1次，6日为1个疗程，共需2个疗程。分别于治疗前、治疗后及治疗后1个月（随访）评估症状总分、健康相关生活质量调查（SF-36）和内皮消化不良指数（NDI）。同时评估疗效。
治疗后，辨证施针组总有效率为87.5%（28/32），优于常规针刺组的74.2%（23/31）和非穴位组的20.7%（6/29）（P<0.05，P<0.01）。与治疗前比较，辨证施针组和常规针刺组治疗后及随访时的SF-36、NDI及症状总分均明显改善（均P<0.05），其中辨证施针组改善最明显[治疗后，SF-36：84.54±5.93对81.44±6.22，63.46±6.59；NDSI：18.94±9.30对21.23±8.39，43.93±11.26；NDLQI：71.42±7.23对63.11±7.06，54.87±6.00；症状总分：22.06±15.80对32.52±16.88，47.97±10.92]；常规针刺组改善明显优于非穴位组（P<0.01，P<0.05）。与治疗前比较，非穴位组治疗后仅NDSI评分改善（P<0.05）。
辨证施针治疗FD能明显提高患者生活质量，是治疗FD的有效疗法。
