Zedan Ahmed H, Vilholm Ole J
Department of Oncology, Lillebaelt Hospital, Vejle, Denmark.
Basic Clin Pharmacol Toxicol. 2014 Aug;115(2):193-200. doi: 10.1111/bcpt.12262. Epub 2014 May 24.
Chemotherapy-induced polyneuropathy (CIPN) is a common, but underestimated, clinical challenge. Incidence varies depending on many factors that are equally as important as the type of chemotherapeutic agent itself. Moreover, the assessment of CIPN is still uncertain, as several of the most frequently used scales do not rely on a formal neurological evaluation and depend on patients' reports and examiners' interpretations. Therefore, the aim of this MiniReview was to introduce the most common chemotherapies that cause neuropathy, and in addition to this, highlight the most significant differences between the neuropathic pain scales, which are most commonly used for assessing CIPN.
化疗引起的周围神经病变（CIPN）是一个常见但被低估的临床挑战。其发病率因许多因素而异，这些因素与化疗药物本身的类型同样重要。此外，CIPN的评估仍不明确，因为一些最常用的量表并不依赖于正式的神经学评估，而是取决于患者的报告和检查者的解读。因此，本综述的目的是介绍导致神经病变的最常见化疗方法，并在此基础上突出用于评估CIPN的最常用神经病理性疼痛量表之间的最显著差异。
