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肝移植围手术期肾脏保护策略

Perioperative renal protection strategies in liver transplantation.

作者信息

Guerrero-Domínguez Rosana, López-Herrera Rodríguez Daniel, Acosta-Martínez Jesús, Bueno-Pérez María, Jiménez Ignacio

出版信息

Nefrologia. 2014 May 21;34(3):276-84. doi: 10.3265/Nefrologia.pre2014.Feb.12409. Epub 2014 Apr 11.

Abstract

Renal failure is one of the most common and major complications in liver transplant recipients. It has been reported to occur at an incidence of 17% to 95%. This complication is associated with prolonged hospital stay in the intensive care unit, the need for postoperative dialysis, infectious complications, acute rejection, and increased mortality. The causes of renal function deterioration differ in the preoperative and postoperative periods. By identifying patients at risk of developing chronic renal failure and by implementing strategies for renal protection at an early stage, it is possible to slow down the progression of renal failure and improve the long-term outcomes in liver transplant recipients.

摘要

肾衰竭是肝移植受者中最常见且最主要的并发症之一。据报道,其发生率为17%至95%。这种并发症与在重症监护病房住院时间延长、术后需要透析、感染性并发症、急性排斥反应以及死亡率增加有关。术前和术后肾功能恶化的原因有所不同。通过识别有发生慢性肾衰竭风险的患者,并在早期实施肾脏保护策略,有可能减缓肾衰竭的进展并改善肝移植受者的长期预后。

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