Division of Gastroenterology, Duke University Medical Center, Durham, NC.
Division of Gastroenterology, Hepatology, and Nutrition, University of Louisville School of Medicine, Louisville, KY.
Chest. 2014 May;145(5):1148-1157. doi: 10.1378/chest.13-1158.
Providing artificial nutrition is an important part of caring for critically ill patients. However, because of a paucity of robust data, the practice has been highly variable and often based more on dogma than evidence. A number of studies have been published investigating many different aspects of critical care nutrition. Although the influx of data has better informed the practice, the results have often been conflicting or counter to prevailing thought, resulting in discordant opinions and different interpretations by experts in the field. In this article, we review and summarize the data from a number of the published studies, including studies investigating enteral vs parenteral nutrition, supplementing enteral with parenteral nutrition, and use of immunonutrition. In addition, published studies informing the practice of how best to provide enteral nutrition will be reviewed, including the use of trophic feedings, gastric residual volumes, and gastric vs postpyloric tube placement.
提供人工营养是危重症患者护理的重要组成部分。然而,由于缺乏强有力的数据,该实践的变化很大,往往更多地基于教条而不是证据。已经发表了许多研究来调查重症监护营养的许多不同方面。尽管数据的涌入更好地为实践提供了信息,但结果往往相互矛盾或与流行的观点相悖,导致该领域的专家意见不一致和不同的解释。在本文中,我们回顾和总结了一些已发表研究的数据,包括研究肠内营养与肠外营养、肠内营养补充肠外营养以及免疫营养的研究。此外,还将回顾发表的研究如何最好地提供肠内营养的实践,包括使用营养喂养、胃残留量以及胃与幽门后管放置。