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使用实时聚合酶链反应作为感染预防工具检测医院员工中腺病毒性结膜炎的情况及患病率

Detection and prevalence of adenoviral conjunctivitis among hospital employees using real-time polymerase chain reaction as an infection prevention tool.

作者信息

Kuo Irene C, Espinosa Colleen, Forman Michael, Pehar Miriana, Maragakis Lisa L, Valsamakis Alexandra

机构信息

Wilmer Eye Institute, Department of Ophthalmology, Johns Hopkins University School of Medicine, Baltimore, Maryland.

出版信息

Infect Control Hosp Epidemiol. 2014 Jun;35(6):728-31. doi: 10.1086/676428. Epub 2014 Apr 23.

DOI:10.1086/676428
PMID:24799652
Abstract

Hospital employees with suspected adenoviral conjunctivitis underwent evaluation and testing with real-time polymerase chain reaction. Viral conjunctivitis was suspected in 307 (59%) of 518 employees with eye complaints; adenovirus was detected in 4% (22 of 518). Four employees had genotypes consistent with epidemic keratoconjunctivitis. This algorithm minimizes productivity loss compared with clinical diagnosis.

摘要

疑似腺病毒性结膜炎的医院员工接受了实时聚合酶链反应评估和检测。在518名有眼部不适的员工中,307名(59%)疑似病毒性结膜炎;518名员工中有4%(22名)检测出腺病毒。4名员工的基因型与流行性角结膜炎一致。与临床诊断相比,该算法将生产力损失降至最低。

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引用本文的文献

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Cost Savings From a Policy to Diagnose and Prevent Transmission of Adenoviral Conjunctivitis in Employees of a Large Academic Medical Center.从一项在大型学术医疗中心员工中诊断和预防腺病毒结膜炎传播的政策中节省成本。
JAMA Ophthalmol. 2021 May 1;139(5):518-524. doi: 10.1001/jamaophthalmol.2021.0150.
2
Determinants of Outcomes of Adenoviral Keratoconjunctivitis.腺病毒性角结膜炎结局的影响因素。
Ophthalmology. 2018 Sep;125(9):1344-1353. doi: 10.1016/j.ophtha.2018.02.016. Epub 2018 Mar 27.
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Adenovirus: Epidemiology, Global Spread of Novel Serotypes, and Advances in Treatment and Prevention.
腺病毒:流行病学、新型血清型的全球传播以及治疗与预防的进展
Semin Respir Crit Care Med. 2016 Aug;37(4):586-602. doi: 10.1055/s-0036-1584923. Epub 2016 Aug 3.