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结晶酚治疗藏毛疾病可改善生活质量。

Crystallized phenol treatment of pilonidal disease improves quality of life.

作者信息

Topuz Omer, Sözen Selim, Tükenmez Mustafa, Topuz Sezgin, Vurdem Umit Erkan

机构信息

Kayseri Training and Teaching Hospital, General Surgery Clinic, Kayseri, Turkey.

Bitlis State Hospital, General Surgery Clinic, Bitlis, Turkey.

出版信息

Indian J Surg. 2014 Feb;76(1):81-4. doi: 10.1007/s12262-012-0610-9. Epub 2012 Jun 29.

Abstract

The effects of crystallized phenol treatment of pilonidal sinus on quality of life has not been investigated before. This study aimed to compare the phenol treatment with surgical excision plus primary closure technique in terms of life quality by means of a life quality questionnaire. This is a prospective randomized clinical study. The study was conducted at Training and Teaching Hospital, Kayseri, Turkey. In total, 40 patients with pilonidal disease were randomly assigned into 2 clinically comparable groups between September 2010 and June 2011. Cristallyzed phenol application was done to 20 patients and surgical excision plus primary closure was done to 20 patients for the treatment of pilonidal disease. Data regarding demographic variables were recorded. To evaluate quality of life and patient comfort all patients asked to fill the questionnaire after complete healing occurred. There was no difference between the groups in age, sex and occupation. Two of the 20 patients in the excision and primary closure group had complication of wound dehiscience and needed prolonged wound care. There was significant differences in favor of the phenol group in all terms of life quality except for complete healing time. As a first degree treatment, phenol treatment is better than the other treatment choices of pilonidal disease in terms of time off work perioperative pain, being away from school and social life. Also phenol treatment can be done without any pretreatment laboratory examination. Further studies will be needed about cost-effectivity of phenol treatment.

摘要

之前尚未研究过结晶酚治疗藏毛窦对生活质量的影响。本研究旨在通过生活质量问卷,在生活质量方面比较酚治疗与手术切除加一期缝合技术。这是一项前瞻性随机临床研究。该研究在土耳其开塞利培训与教学医院进行。2010年9月至2011年6月期间,共40例藏毛疾病患者被随机分为2个临床可比组。对20例患者进行结晶酚治疗,对20例患者进行手术切除加一期缝合治疗藏毛疾病。记录了人口统计学变量数据。为评估生活质量和患者舒适度,所有患者在完全愈合后被要求填写问卷。两组在年龄、性别和职业方面无差异。切除加一期缝合组的20例患者中有2例出现伤口裂开并发症,需要延长伤口护理时间。除完全愈合时间外,在生活质量的所有方面,酚治疗组均有显著优势。作为一级治疗,酚治疗在围手术期疼痛、误工时间、缺课时间和社交生活方面比藏毛疾病的其他治疗选择更好。而且酚治疗无需任何预处理实验室检查即可进行。关于酚治疗的成本效益还需要进一步研究。

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