Vlasov L E, Gapanovich S E, Pilotovich V S, Slizskiĭ S I
Ter Arkh. 1989;61(7):73-5.
During hemodialysis, 44 patients with terminal chronic renal failure were examined for the systemic hemodynamics and blood rheological properties as well as for the possibility of their correction by infusion of the plasma substitutes: polyglucine, rondex or 10% albumin at a volume of 400 ml per administration. It was established that patients on hemodialysis manifested pronounced hemodynamic and rheological disorders. During hemodialysis, the hemodynamic disorders correlated with the changes in the rheological properties of the blood (r = 0.23-0.45, p less than 0.05). It is indicated that to treat the hypotensive states occurring in the course of hemodialysis, infusions of the plasma expanders, rondex, 10% albumin and polyglucine may be used at a limited volume. The plasma substitute rondex ensures a more favorable hemodynamic and rheological effect, comparing very favourably with other preparations investigated.
在血液透析期间，对44例终末期慢性肾衰竭患者进行了全身血流动力学和血液流变学特性检查，以及通过输注血浆代用品（每剂400毫升的聚明胶肽、羟乙基淀粉或10%白蛋白）来纠正这些特性的可能性研究。结果表明，进行血液透析的患者表现出明显的血流动力学和流变学紊乱。在血液透析期间，血流动力学紊乱与血液流变学特性的变化相关（r = 0.23 - 0.45，p < 0.05）。结果表明，为治疗血液透析过程中出现的低血压状态，可使用有限体积的血浆扩容剂、羟乙基淀粉、10%白蛋白和聚明胶肽进行输注。与所研究的其他制剂相比，血浆代用品羟乙基淀粉能确保更有利的血流动力学和流变学效果。
