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[兔血T淋巴细胞在对异种红细胞免疫应答过程中的抗原特异性辅助和抑制活性]

[Antigen-specific helper and suppressor activities of T-lymphocytes of the rabbit blood during the development of immunologic response to heterologous erythrocytes].

作者信息

Bryzgina T M, Martynova T V, Alekseeva I N

出版信息

Fiziol Zh (1978). 1989 Sep-Oct;35(5):54-8.

PMID:2480252
Abstract

A titre of hemolysins in blood serum, helper and suppressor activity of blood T-lymphocytes in response of ++blast transformation to Con A in different doses (8 and 60 ml) and was determined in rabbits after single and two-fold (with an interval of 30 days) immunization of the ram erythrocytes. Examinations were conducted 2, 9, 16 and 30 days after antigen introduction. Peculiarities of changes in antigen-specific helper and suppressor activity of lymphocytes and their balance in dynamics of primary and secondary immune responses are determined.

摘要

测定了兔单次及两次(间隔30天)免疫公羊红细胞后血清中溶血素的效价、血液T淋巴细胞在不同剂量(8和60微克)刀豆蛋白A刺激下的增殖转化反应中的辅助和抑制活性。在抗原注入后第2、9、16和30天进行检测。确定了淋巴细胞抗原特异性辅助和抑制活性变化的特点及其在初次和二次免疫反应动态中的平衡。

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