甲胎蛋白与纵隔生殖细胞肿瘤

Alpha-fetoprotein and mediastinal germ cell tumors.

作者信息

Rapellino M, Cellerino A, Ardissone F, Libertucci D, Coni F, Aimo G, Pecchio F

出版信息

J Nucl Med Allied Sci. 1989 Jul-Sep;33(3 Suppl):46-52.

Abstract

The Authors discuss the utility of alpha-fetoprotein (AFP) determination in mediastinal dysembryomas. AFP should be determined in all cases of mediastinal lesion. High levels of up to 500 ng/ml are a sure sign of germ cell tumors. An extremely high level (greater than 1,000 ng/ml) is an indication that the lesion is a mesoblastoma. An increase in the AFP level in the follow-up of patients affected by germ cell tumors is a sure sign of the recurrence of the disease.

摘要

作者讨论了甲胎蛋白（AFP）测定在纵隔胚胎瘤中的应用。所有纵隔病变病例均应测定AFP。高达500 ng/ml的高水平是生殖细胞瘤的明确标志。极高水平（大于1000 ng/ml）表明病变是成神经细胞瘤。生殖细胞瘤患者随访中AFP水平升高是疾病复发的明确标志。