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中国河南临床分离鲍曼不动杆菌和铜绿假单胞菌中质粒介导喹诺酮耐药基因的出现。

Emergence of plasmid-mediated quinolone resistance genes in clinical isolates of Acinetobacter baumannii and Pseudomonas aeruginosa in Henan, China.

机构信息

College of Life Sciences, Henan Normal University, Xinxiang 453007, China.

Department of Chemistry and Chemical Engineering, Xinxiang University, Xinxiang 453000, China.

出版信息

Diagn Microbiol Infect Dis. 2014 Jul;79(3):381-3. doi: 10.1016/j.diagmicrobio.2014.03.025. Epub 2014 Apr 12.

Abstract

A total of 216 clinical isolates of Acinetobacter baumannii and Pseudomonas aeruginosa were collected from a general hospital in Henan, China, and screened for the plasmid-mediated quinolone resistance (PMQR) determinants. The presence of β-lactamase genes and mutations in quinolone resistance-determining regions were investigated among the PMQR-positive isolates.

摘要

共收集了来自中国河南某综合医院的 216 株鲍曼不动杆菌和铜绿假单胞菌临床分离株,并对其进行了质粒介导的喹诺酮类耐药性(PMQR)决定因素的筛选。对 PMQR 阳性分离株中的β-内酰胺酶基因和喹诺酮类耐药决定区突变进行了研究。

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