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冠状动脉搭桥术后的手术状态与生存率

Operative status and survival after coronary artery bypass grafting.

作者信息

Efird Jimmy T, O'Neal Wesley T, Davies Stephen W, O'Neal Jason B, Chitwood W Randolph, Ferguson T Bruce, Kypson Alan P

机构信息

East Carolina Heart Institute, Department of Cardiovascular Sciences, East Carolina University, Greenville, NC Center for Health Disparities, Brody School of Medicine, East Carolina University, Greenville, NC.

Department of Internal Medicine, Wake Forest University School of Medicine, Winston-Salem, NC.

出版信息

Heart Surg Forum. 2014 Apr;17(2):E82-90. doi: 10.1532/HSF98.2013310.

DOI:10.1532/HSF98.2013310
PMID:24808447
Abstract

BACKGROUND

The effect of race on long-term survival of patients undergoing elective and nonelective coronary artery bypass grafting (CABG) is currently unknown. The purpose of this study was to compare long-term survival between black and white CABG patients by operative status.

METHODS

Long-term survival of black versus white patients undergoing elective and nonelective CABG procedures between 1992 and 2011 was compared. Survival probabilities were computed using the Kaplan-Meier product-limit method and stratified by race. Hazard ratios (HR) and 95% confidence intervals (CI) were computed using a Cox regression model.

RESULTS

A total of 13,774 patients were included in this study. The median follow-up time for study participants was 8.2 years. Black patients undergoing elective CABG died sooner than whites (adjusted HR = 1.4, 95% CI = 1.2-1.5). Survival was similar between blacks and whites in the nonelective population (adjusted HR = 1.0, 95% CI = 0.96-1.1).

CONCLUSIONS

Black race was a statistically significant predictor of long-term survival after elective but not nonelective CABG.

摘要

背景

种族对接受择期和非择期冠状动脉旁路移植术(CABG)患者长期生存的影响目前尚不清楚。本研究的目的是按手术状态比较黑人和白人CABG患者的长期生存率。

方法

比较了1992年至2011年间接受择期和非择期CABG手术的黑人和白人患者的长期生存率。使用Kaplan-Meier乘积限界法计算生存概率,并按种族分层。使用Cox回归模型计算风险比(HR)和95%置信区间(CI)。

结果

本研究共纳入13774例患者。研究参与者的中位随访时间为8.2年。接受择期CABG的黑人患者比白人死亡更早(校正HR = 1.4,95%CI = 1.2 - 1.5)。非择期人群中黑人和白人的生存率相似(校正HR = 1.0,95%CI = 0.96 - 1.1)。

结论

黑人种族是择期而非非择期CABG术后长期生存的统计学显著预测因素。

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