Yang Zhiping, Wu Qiong, Wu Kaichun, Fan Daiming
Xijing Hospital of Digestive Diseases, Xijing Hospital, Fourth Military Medical University, 127 West Changle Road, Xi'an, China.
Expert Rev Gastroenterol Hepatol. 2014 Sep;8(7):811-8. doi: 10.1586/17474124.2014.917958. Epub 2014 May 9.
Surgical treatment does not cure Crohn's disease, and postoperative recurrence is a feature of the clinical course of the disease. Ileocolonoscopy remains the gold standard for the surveillance of recurrent Crohn's disease and should be performed 6-12 months after an operation. Many other non-invasive techniques are also useful and complement endoscopy for the early diagnosis of postoperative recurrence. Anti-TNF agents show great efficacy for the prevention of postoperative recurrence, and long-term use can maintain remission. It remains undetermined whether early treatment after postoperative endoscopic recurrence is ultimately as efficacious as prophylactic therapy.
手术治疗无法治愈克罗恩病，术后复发是该疾病临床病程的一个特征。结肠结肠镜检查仍是监测复发性克罗恩病的金标准，应在术后6至12个月进行。许多其他非侵入性技术也很有用，可辅助内镜检查用于术后复发的早期诊断。抗TNF药物对预防术后复发显示出巨大疗效，长期使用可维持缓解状态。术后内镜复发后早期治疗是否最终与预防性治疗同样有效仍未确定。
