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在中国南方猪群中鉴定出四种H3N2型猪流感病毒基因型。

Identification of four genotypes of H3N2 swine influenza virus in pigs from southern China.

作者信息

Chen Jidang, Fu Xinliang, Chen Ye, He Shuyi, Zheng Yun, Cao Zhenpeng, Yu Wenxin, Zhou Han, Su Shuo, Zhang Guihong

机构信息

MOA Key Laboratory of Animal Vaccine Development, Ministry of China, South China Agricultural University, Guangzhou, 510642, Guangdong, People's Republic of China.

出版信息

Arch Virol. 2014 Oct;159(10):2705-9. doi: 10.1007/s00705-014-2040-4. Epub 2014 May 9.

Abstract

In 2011, four H3N2 swine influenza viruses (SIVs) were isolated from nasal swabs of four pigs (800 nasal swabs were collected from pigs showing influenza-like symptoms) in Guangdong province, China. Four different genotypes of H3N2 appeared among pigs in southern China, including wholly human-like H3N2 viruses, intermediate (1975) double-reassortant human H3N2 viruses (resulting from reassortment between an early human lineage and a recent human lineage), recent double-reassortant human H3N2 viruses, and avian-like H3N2 viruses. Because pigs can support the reassortment of human and avian influenza viruses, our surveillance should be enhanced as a part of an overall pandemic preparedness plan.

摘要

2011年,从中国广东省4头猪的鼻拭子中分离出4株H3N2猪流感病毒(共采集了800份表现出流感样症状猪的鼻拭子)。中国南方猪群中出现了4种不同基因型的H3N2,包括完全类人H3N2病毒、中间型(1975)双重配型人H3N2病毒(由早期人类谱系和近期人类谱系之间的重配产生)、近期双重配型人H3N2病毒以及禽样H3N2病毒。由于猪能够支持人类和禽流感病毒的重配,作为整体大流行防范计划的一部分,我们应加强监测。

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