Bonadonna G, Valagussa P, Santoro A, Viviani S, Bonfante V, Banfi A
Divisions of Medical Oncology, Istituto Nazionale Tumori, Milan, Italy.
Recent Results Cancer Res. 1989;117:169-74. doi: 10.1007/978-3-642-83781-4_17.
The report includes the essential therapeutic and toxic results following MOPP vs. MOPP/ABVD and MOPP vs. ABVD within a combined modality setting. The findings indicate that in stage IV the alternating regimen is superior to MOPP while in stage IIB-III ABVD plus radiotherapy yielded superior results associated with no treatment-induced sterility and leukemia compared with MOPP plus radiotherapy.
该报告涵盖了在综合治疗模式下，MOPP方案与MOPP/ABVD方案对比以及MOPP方案与ABVD方案对比后的基本治疗效果和毒性结果。研究结果表明，在IV期，交替方案优于MOPP方案；而在IIB - III期，与MOPP加放疗相比，ABVD加放疗产生了更好的效果，且没有治疗引起的不育和白血病问题。
