Garber J E, Henderson I C
Clinical Epidemiology Branch, National Cancer Institute, Boston, Massachusetts.
Hematol Oncol Clin North Am. 1989 Dec;3(4):807-21.
Recurrent breast cancer is incurable. Chemotherapeutic agents will be used in most patients with metastatic disease at some time during their course. There is little evidence that such agents prolong survival, and their toxicities are not inconsiderable. The focus of treatment should be on the palliation of symptoms. Single-agent regimens should not be assumed to be less effective than combinations, particularly as salvage therapies. Some new approaches to the management of metastatic disease are explored.
复发性乳腺癌无法治愈。大多数转移性疾病患者在病程中的某个阶段会使用化疗药物。几乎没有证据表明这些药物能延长生存期，而且它们的毒性也不容小觑。治疗的重点应是缓解症状。不应认为单药治疗方案比联合治疗方案效果差，尤其是作为挽救性治疗时。本文探讨了一些转移性疾病管理的新方法。
