Meinel Felix G, Canstein Christian, Schoepf U Joseph, Sedlmaier Martin, Schmidt Bernhard, Harris Brett S, Flohr Thomas G, De Cecco Carlo N
Department of Radiology and Radiological Science, Medical University of South Carolina, Ashley River Tower, 25 Courtenay Drive, Charleston, SC, 29425-2260, USA.
Eur Radiol. 2014 Jul;24(7):1643-50. doi: 10.1007/s00330-014-3194-x. Epub 2014 May 10.
To assess the influence of tube potential on radiation dose and image quality of third-generation dual-source coronary CT angiography (CTA) in a phantom simulating an obese patient.
A thoracic phantom was equipped with tubular inserts containing iodine solution and water. A soft-tissue-equivalent ring around the phantom simulated an obese patient. Images were acquired at tube potentials of 80, 100, 120 and 140 kV with second-generation dual-source CT (DSCT) and 70-150 kV (in 10-kV increments) with third-generation DSCT. Contrast-to-noise ratio (CNR) was calculated and CT dose index was recorded.
With second-generation DSCT, CNR was highest for 120 kV (19.0) and decreased with lower tube potential (12.0 at 80 kV) owing to disproportionately increased image noise. With third-generation DSCT, 70- and 80-kV acquisitions showed a smaller increase in noise. CNRs for third-generation DSCT were highest for 70 and 80 kV (21.1 and 21.2, respectively). Compared to 120 kV, radiation dose was 68% and 49% lower at 70 kV and 80 kV, respectively.
Third-generation DSCT enables one to perform coronary CTA at 70-80 kV in obese patients without compromising CNR and thus reduces radiation dose by 49-68%.
• Low tube potential CT angiography is currently not suitable for obese patients. • Third-generation DSCT offers substantially increased tube power at low tube potential. • This enables one to perform coronary CT angiography at 70-80 kV in obese patients. • Signal-to-noise ratio is maintained owing to increased tube current. • This approach can be expected to reduce radiation dose by 49-68%.
在模拟肥胖患者的体模中评估管电压对第三代双源冠状动脉CT血管造影(CTA)辐射剂量及图像质量的影响。
一个胸部体模配备了装有碘溶液和水的管状插入物。体模周围的软组织等效环模拟肥胖患者。使用第二代双源CT(DSCT)在80、100、120和140 kV的管电压下采集图像,使用第三代DSCT在70 - 150 kV(以10 kV为增量)下采集图像。计算对比噪声比(CNR)并记录CT剂量指数。
使用第二代DSCT时,120 kV的CNR最高(19.0),由于图像噪声不成比例增加,较低管电压时CNR降低(80 kV时为12.0)。使用第三代DSCT时,70 kV和80 kV采集的噪声增加较小。第三代DSCT在70 kV和80 kV时的CNR最高(分别为21.1和21.2)。与120 kV相比,70 kV和80 kV时的辐射剂量分别降低了68%和49%。
第三代DSCT能够在肥胖患者中于70 - 80 kV下进行冠状动脉CTA,而不影响CNR,从而将辐射剂量降低49% - 68%。
• 低管电压CT血管造影目前不适用于肥胖患者。• 第三代DSCT在低管电压下提供了显著增加的管功率。• 这使得能够在肥胖患者中于70 - 80 kV下进行冠状动脉CT血管造影。• 由于管电流增加,信噪比得以维持。• 预计这种方法可将辐射剂量降低49% - 68%。