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联合应用明矾钾硫酸酯和鞣酸硬化疗法以及使用弹性人工韧带进行肛门环缩术治疗直肠脱垂。

Combined aluminum potassium sulfate and tannic acid sclerosing therapy and anal encirclement using an elastic artificial ligament for rectal prolapse.

机构信息

Department of Proctology, Kunimoto Hospital, Asahikawa, Japan.

出版信息

Dis Colon Rectum. 2014 May;57(5):653-7. doi: 10.1097/DCR.0000000000000087.

Abstract

BACKGROUND

Aluminum potassium sulfate and tannic acid is a sclerosant used for sclerosing therapy in the treatment of hemorrhoids, and a Leeds-Keio artificial ligament is a new anal-encircling material for the management of rectal prolapse.

OBJECTIVE

The aim of this study was to evaluate clinical data and recurrence rates in patients with rectal prolapse undergoing combined aluminum potassium sulfate and tannic acid injection and anal encirclement using the Leeds-Keio artificial ligament.

DESIGN

This was a retrospective review of patients who underwent this procedure.

SETTINGS

This study was conducted at a community-based hospital within a specialized colorectal unit.

PATIENTS

A total of 23 patients (20 women; median age, 83 years) with full-thickness rectal prolapse underwent treatment between 2005 and 2010.

MAIN OUTCOME MEASURES

The main outcome measures were morbidity and recurrence rate.

RESULTS

The median duration of surgery was 36 minutes. Mean total injection dose of aluminum potassium sulfate and tannic acid was 30 mL. There were no postoperative deaths. Wound infection occurred in 2 patients (9%), and new or worsening symptoms of constipation after surgery occurred in 6 patients (26%). There were 3 recurrences at a median follow-up of 36 months (range, 7-86 months). Recurrence rate at 5 years was 14% (95% CI, 5%-35%).

LIMITATIONS

The limitations of this study include its retrospective nature, the potential for selection bias, and lack of a control group.

CONCLUSIONS

This procedure is quick and easy to perform, with no formidable morbidity, and the recurrence rate is reasonably low. Therefore, it seems to be a reasonable alternative for rectal prolapse in frail, elderly, and high-risk patients.

摘要

背景

明矾钾和鞣酸是一种用于硬化疗法治疗痔疮的硬化剂,而 Leeds-Keio 人工韧带是一种用于直肠前突管理的新型肛门环绕材料。

目的

本研究旨在评估接受明矾钾和鞣酸注射联合 Leeds-Keio 人工韧带肛门环绕治疗的直肠前突患者的临床数据和复发率。

设计

这是一项对接受该手术的患者进行的回顾性研究。

设置

本研究在一家社区医院的专门结直肠科进行。

患者

共有 23 名(20 名女性;中位年龄 83 岁)完全性直肠前突患者于 2005 年至 2010 年接受治疗。

主要观察指标

主要观察指标为发病率和复发率。

结果

手术中位时间为 36 分钟。明矾钾和鞣酸的平均总注射剂量为 30 mL。无术后死亡。2 例(9%)发生伤口感染,6 例(26%)术后出现新的或加重的便秘症状。中位随访 36 个月(范围 7-86 个月)时发生 3 例复发。5 年复发率为 14%(95%CI,5%-35%)。

局限性

本研究的局限性包括其回顾性性质、潜在的选择偏倚以及缺乏对照组。

结论

该手术快速简便,发病率低,复发率合理。因此,对于虚弱、老年和高危患者的直肠前突,它似乎是一种合理的替代方法。

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