Busch Andrew M, Scott-Sheldon Lori A J, Pierce Jacqueline, Chattillion Elizabeth A, Cunningham Karlene, Buckley Maria L, Mazer Jeffrey M, Blaney Cerissa L, Carey Michael P
The Miriam Hospital, USA; Alpert Medical School of Brown University, USA.
The Miriam Hospital, USA; Alpert Medical School of Brown University, USA; Brown University School of Public Health, USA.
Respir Med. 2014 Jul;108(7):1007-13. doi: 10.1016/j.rmed.2014.04.010. Epub 2014 Apr 26.
As many as 30% of patients who start pulmonary rehabilitation (PR) fail to complete it, and depressed mood has been associated with PR non-completion. Depression is more common in women than men with COPD and historically women with COPD have been under studied. However, no studies to date have investigated gender-specific predictors of PR completion.
The study included 111 patients with COPD who enrolled in a community based outpatient PR program in Providence, RI. Patients who attended 20 or more sessions were designated "completers". Depression was measured using the CES-D. Logistic regression models were evaluated to test depressed mood as a predictor of PR completion. Analyses controlled for demographic and health variables found to differ between completers and non-completers.
Patients were 95% white and 49.5% women, and 74% had a GOLD stage ≥3. Sixty-eight percent of patients were PR completers. A logistic regression model, showed that lower depressed mood independently predicted PR completion across all patients (adjusted OR = 0.92, p = .002). In gender-stratified analyses, lower depressed mood was an independent predictor of PR completion for women (adjusted OR = .91, p = .024) but not men (adjusted OR = .97, p = .45). Greater 6-min walk test distance was also an independent predictor of PR completion among women.
Depressed mood is an important predictor of completion of community based PR among women. Screening and brief treatment of depression should be considered in practice.
开始进行肺康复(PR)的患者中,多达30%未能完成康复治疗,而情绪低落与未完成肺康复治疗有关。在慢性阻塞性肺疾病(COPD)患者中,女性比男性更容易出现抑郁,而且历来对患有COPD的女性研究较少。然而,迄今为止尚无研究调查肺康复完成情况的性别特异性预测因素。
该研究纳入了111名患有COPD的患者,他们参加了罗德岛州普罗维登斯市一个基于社区的门诊肺康复项目。参加20次或更多次治疗的患者被指定为“完成者”。使用流调中心抑郁量表(CES-D)测量抑郁情况。对逻辑回归模型进行评估,以检验情绪低落是否为肺康复完成情况的预测因素。分析对完成者和未完成者之间存在差异的人口统计学和健康变量进行了控制。
患者中95%为白人,49.5%为女性,74%的患者全球慢性阻塞性肺疾病倡议(GOLD)分级≥3级。68%的患者完成了肺康复治疗。一个逻辑回归模型显示,在所有患者中,较低的抑郁情绪独立预测肺康复的完成情况(调整后的比值比[OR]=0.92,p=0.002)。在按性别分层的分析中,较低的抑郁情绪是女性肺康复完成情况的独立预测因素(调整后的OR=0.91,p=0.024),但不是男性的独立预测因素(调整后的OR=0.97,p=0.45)。更长的6分钟步行试验距离也是女性肺康复完成情况的独立预测因素。
情绪低落是女性完成基于社区的肺康复治疗的重要预测因素。在实践中应考虑对抑郁进行筛查和简短治疗。