[消癃灵制剂对小鼠实验性前列腺增生的影响]

[Effects of the preparation of xiao long ling on experimental prostatic hyperplasia in mice].

作者信息

Deng H Z, Zhang C H, Cheng Y H, Li J Z, Yang X H, Wang G J

出版信息

Zhongguo Zhong Yao Za Zhi. 1989 Jul;14(7):428-31, 448.

PMID:2482033

Abstract

The results of the experiments indicate that the prostatic hyperplasia caused by Testosteroni Propionatis in mice, cotton oil-induced local swollen ears of mice and the proliferation of granuloma produced by subcutaneous implantation of cotton pill in rats are inhibited significantly by the preparation of Xiao Long Ling. Xiao Long Ling depresses the increase of vascular permeability induced by a variety of inflammatory media such as histamine, 5-HT and PGE. Xiao Long Ling is found capable of inhibiting the platelet aggregation induced by ADP as well as depolymerizing the aggregated platelets.

摘要

实验结果表明，消癃灵制剂能显著抑制丙酸睾酮所致小鼠前列腺增生、棉油所致小鼠耳局部肿胀及大鼠棉球皮下埋藏所致肉芽肿增生。消癃灵能抑制组胺、5-羟色胺、前列腺素E等多种炎症介质所致的血管通透性增加。发现消癃灵能抑制ADP诱导的血小板聚集，并使已聚集的血小板解聚。