Mihatsch M J, Kyo M, Gudat F
Verh Dtsch Ges Pathol. 1989;73:207-32.
This review gives a survey of the most important tubulo-interstitial and glomerular lesions in kidney transplants. Among the tubulo-interstitial lesions subcapsular interstitial fibrosis, acute tubular necrosis, cellular tubulo-interstitial rejection and Ciclosporin associated lesions are briefly described. The review of the glomerular lesions is focused upon intraglomerular coagulation, transplant glomerulitis and transplant glomerulopathy. Among the immunocomplex diseases the preexisting glomerular lesions are stressed. Furthermore the differential diagnosis between rejection associated glomerular lesions and glomerulonephritis is discussed. Finally the prognostic significance of the different morphologic lesions is outlined based on an analysis of 500 biopsies from Basel.
本综述对肾移植中最重要的肾小管间质和肾小球病变进行了概述。在肾小管间质病变中，简要描述了包膜下间质纤维化、急性肾小管坏死、细胞性肾小管间质排斥反应和环孢素相关病变。肾小球病变的综述重点关注肾小球内凝血、移植性肾小球炎和移植性肾小球病。在免疫复合物疾病中，强调了先前存在的肾小球病变。此外，还讨论了排斥反应相关肾小球病变与肾小球肾炎之间的鉴别诊断。最后，基于对巴塞尔500份活检样本的分析，概述了不同形态学病变的预后意义。
