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Platelet CD36 links not only α-granule-derived proteins to thrombus stability but also metabolic and oxidant stress to a prothrombotic phenotype.

作者信息

Silverstein Roy L

机构信息

From the Department of Medicine, Medical College of Wisconsin and Blood Research Institute, Blood Center of Wisconsin, Milwaukee.

出版信息

Arterioscler Thromb Vasc Biol. 2014 Jun;34(6):1120-1. doi: 10.1161/ATVBAHA.114.303687.

DOI:10.1161/ATVBAHA.114.303687
PMID:24828516
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4629480/
Abstract
摘要

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Platelet-derived S100 family member myeloid-related protein-14 regulates thrombosis.血小板衍生 S100 家族成员髓系相关蛋白-14 调节血栓形成。
J Clin Invest. 2014 May;124(5):2160-71. doi: 10.1172/JCI70966. Epub 2014 Apr 1.
2
Supporting roles of platelet thrombospondin-1 and CD36 in thrombus formation on collagen.血小板凝血酶敏感蛋白-1 和 CD36 在胶原诱导的血栓形成中的辅助作用。
Arterioscler Thromb Vasc Biol. 2014 Jun;34(6):1187-92. doi: 10.1161/ATVBAHA.113.302917. Epub 2014 Mar 27.
3
Gray platelet syndrome and defective thrombo-inflammation in Nbeal2-deficient mice.Nbeal2基因缺陷小鼠的灰色血小板综合征与血栓炎症缺陷
J Clin Invest. 2013 Jul 1;123(8):3331-42. doi: 10.1172/JCI69210.
4
Minding the gaps--and the junctions, too.留意间隙——还有连接处。
Circulation. 2012 May 22;125(20):2414-6. doi: 10.1161/CIRCULATIONAHA.112.106377. Epub 2012 Apr 23.
5
Advanced glycation end products induce a prothrombotic phenotype in mice via interaction with platelet CD36.晚期糖基化终产物通过与血小板 CD36 相互作用诱导小鼠形成促血栓表型。
Blood. 2012 Jun 21;119(25):6136-44. doi: 10.1182/blood-2011-10-387506. Epub 2012 Mar 19.
6
Platelet CD36 surface expression levels affect functional responses to oxidized LDL and are associated with inheritance of specific genetic polymorphisms.血小板 CD36 表面表达水平影响对氧化 LDL 的功能反应，并且与特定遗传多态性的遗传有关。
Blood. 2011 Jun 9;117(23):6355-66. doi: 10.1182/blood-2011-02-338582. Epub 2011 Apr 8.
7
Vav guanine nucleotide exchange factors link hyperlipidemia and a prothrombotic state.Vav 鸟嘌呤核苷酸交换因子将高脂血症和血栓前状态联系起来。
Blood. 2011 May 26;117(21):5744-50. doi: 10.1182/blood-2009-01-201970. Epub 2011 Mar 22.
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Platelet CD36 mediates interactions with endothelial cell-derived microparticles and contributes to thrombosis in mice.血小板CD36介导与内皮细胞衍生微粒的相互作用，并促进小鼠血栓形成。
J Clin Invest. 2008 May;118(5):1934-43. doi: 10.1172/JCI34904.
9
Thrombospondin-1 stimulates platelet aggregation by blocking the antithrombotic activity of nitric oxide/cGMP signaling.血小板反应蛋白-1通过阻断一氧化氮/cGMP信号通路的抗血栓形成活性来刺激血小板聚集。
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