Salari Masoumeh, Hosseini Mousareza, Nekooei Sirous, Ataei Azimi Sajad, Farzanehfar Mohammad Reza
Assistant Professor, Department of Internal Medicine, Ghaem Hospital, Mashhad University of Medicine Sciences, Mashhad, Iran.
Assistant Professor, Department of Gasteroenterology and Hepatology, Ghaem Hospital, Mashhad University of Medicine Sciences, Mashhad,Iran.
Middle East J Dig Dis. 2014 Jan;6(1):42-6.
Autoimmune pancreatitis is a fibro-inflammatory form of chronic pancreatitis. It is diagnosed by the combination of imaging studies such as a CT scan and pancreatography, laboratory analyses that include IgG4 and/or autoantibodies, histopathological evaluations and positive response to corticosteroid therapy. We report the case of a 41-year-old female with a history of jaundice and increasing abdominal pain for two weeks prior to her clinic visit. Laboratory results were significant for an increase in alkaline phosphatase (ALP) and erythrocyte sedimentation rate (ESR). Magnetic resonance cholangiopancreatography (MRCP) confirmed areas of stenosis and dilatation in the pancreatic duct and in the intra- and extra-hepatic bile ducts similar to primary sclerosantcholangitis. Laboratory analyses showed increased levels of IgG4 with thepresence of antinuclear antibodies.
自身免疫性胰腺炎是慢性胰腺炎的一种纤维炎症形式。它通过诸如CT扫描和胰管造影等影像学检查、包括IgG4和/或自身抗体的实验室分析、组织病理学评估以及对皮质类固醇治疗的阳性反应来诊断。我们报告一例41岁女性病例，该患者在就诊前两周有黄疸病史且腹痛加重。实验室检查结果显示碱性磷酸酶（ALP）和红细胞沉降率（ESR）升高。磁共振胰胆管造影（MRCP）证实胰管以及肝内和肝外胆管存在狭窄和扩张区域，类似于原发性硬化性胆管炎。实验室分析显示IgG4水平升高且存在抗核抗体。
