Rizvi Asad A, Margey Ronan, Kiernan Francis
Conn Med. 2014 Apr;78(4):215-9.
The case of a 44-year-old female with multiple embolic cerebellar infarcts associated with a "high risk" patent foramen ovale (PFO) is presented. This article reviews current management of PFO in association with cryptogenic stroke in light of the results of three recent randomized controlled trials and two meta-analyses of observational data. The article will also discuss circumstances which merit consideration for closure despite the negative trial data, and will review our management strategy for closure in this patient with a nickel allergy that precluded the use of the most commonly used PFO closure device.
本文介绍了一名44岁女性患者，其患有多发性栓塞性小脑梗死，伴有“高危”卵圆孔未闭（PFO）。本文根据最近三项随机对照试验的结果以及两项观察性数据的荟萃分析，综述了与不明原因卒中相关的PFO的当前治疗方法。本文还将讨论尽管试验数据为阴性但仍值得考虑封堵的情况，并将回顾我们对该镍过敏患者的封堵管理策略，该过敏情况排除了使用最常用的PFO封堵装置。
