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Helper T cell plasticity: impact of extrinsic and intrinsic signals on transcriptomes and epigenomes.
Curr Top Microbiol Immunol. 2014;381:279-326. doi: 10.1007/82_2014_371.
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Transcriptional and epigenetic control of T helper cell specification: molecular mechanisms underlying commitment and plasticity.
Annu Rev Immunol. 2012;30:707-31. doi: 10.1146/annurev-immunol-020711-075058. Epub 2012 Jan 6.
3
Helper T-cell identity and evolution of differential transcriptomes and epigenomes.
Immunol Rev. 2013 Mar;252(1):24-40. doi: 10.1111/imr.12037.
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Transcriptional and epigenetic networks of helper T and innate lymphoid cells.
Immunol Rev. 2014 Sep;261(1):23-49. doi: 10.1111/imr.12208.
5
Helper T-cell differentiation and plasticity: insights from epigenetics.
Immunology. 2011 Nov;134(3):235-45. doi: 10.1111/j.1365-2567.2011.03483.x.
6
Transcriptional and epigenetic regulation of follicular T-helper cells and their role in autoimmunity.
Autoimmunity. 2017 Mar;50(2):71-81. doi: 10.1080/08916934.2017.1284821. Epub 2017 Feb 21.
8
Transcription factor interplay in T helper cell differentiation.
Brief Funct Genomics. 2013 Nov;12(6):499-511. doi: 10.1093/bfgp/elt025. Epub 2013 Jul 22.
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Transcription tipping points for T follicular helper cell and T-helper 1 cell fate commitment.
Cell Mol Immunol. 2021 Mar;18(3):528-538. doi: 10.1038/s41423-020-00554-y. Epub 2020 Sep 30.

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Aiolos promotes CXCR3 expression on Th1 cells via positive regulation of IFN-γ/STAT1 signaling.
JCI Insight. 2024 Nov 19;10(1):e180287. doi: 10.1172/jci.insight.180287.
2
Plasticity and lineage commitment of individual T1 cells are determined by stable T-bet expression quantities.
Sci Adv. 2024 Jun 7;10(23):eadk2693. doi: 10.1126/sciadv.adk2693. Epub 2024 Jun 5.
3
Eos Promotes TH2 Differentiation by Interacting with and Propagating the Activity of STAT5.
J Immunol. 2023 Aug 1;211(3):365-376. doi: 10.4049/jimmunol.2200861.
4
Human CCR6+ Th Cells Show Both an Extended Stable Gradient of Th17 Activity and Imprinted Plasticity.
J Immunol. 2023 Jun 1;210(11):1700-1716. doi: 10.4049/jimmunol.2200874.
5
Human CCR6 Th cells show both an extended stable gradient of Th17 activity and imprinted plasticity.
bioRxiv. 2023 Jan 6:2023.01.05.522630. doi: 10.1101/2023.01.05.522630.
6
The Interplay of Transcription and Genome Topology Programs T Cell Development and Differentiation.
J Immunol. 2022 Dec 15;209(12):2269-2278. doi: 10.4049/jimmunol.2200625.
7
Signaling networks controlling ID and E protein activity in T cell differentiation and function.
Front Immunol. 2022 Aug 2;13:964581. doi: 10.3389/fimmu.2022.964581. eCollection 2022.
8
Mapping the landscape of chromatin dynamics during naïve CD4+ T-cell activation.
Sci Rep. 2021 Jul 8;11(1):14101. doi: 10.1038/s41598-021-93509-w.
9
Evasion of Immunological Memory by Infection: Implications for Vaccine Design.
Front Immunol. 2021 Feb 22;12:633672. doi: 10.3389/fimmu.2021.633672. eCollection 2021.
10
Cytokine-regulated Th17 plasticity in human health and diseases.
Immunology. 2021 May;163(1):3-18. doi: 10.1111/imm.13280. Epub 2020 Nov 6.

本文引用的文献

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Stimulus-triggered fate conversion of somatic cells into pluripotency.
Nature. 2014 Jan 30;505(7485):641-7. doi: 10.1038/nature12968.
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Pathogenic conversion of Foxp3+ T cells into TH17 cells in autoimmune arthritis.
Nat Med. 2014 Jan;20(1):62-8. doi: 10.1038/nm.3432. Epub 2013 Dec 22.
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A special population of regulatory T cells potentiates muscle repair.
Cell. 2013 Dec 5;155(6):1282-95. doi: 10.1016/j.cell.2013.10.054.
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Metabolites produced by commensal bacteria promote peripheral regulatory T-cell generation.
Nature. 2013 Dec 19;504(7480):451-5. doi: 10.1038/nature12726. Epub 2013 Nov 13.
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Commensal microbe-derived butyrate induces the differentiation of colonic regulatory T cells.
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