Castro-Rodriguez Jose A, Giubergia Veronica, Fischer Gilberto B, Castaños Claudio, Sarria Edgar E, Gonzalez Ramiro, Mattiello Rita, Vega-Briceño Luis E, Murtagh Patricia
Pulmonology Unit, Departments of Pediatrics, School of Medicine, Pontificia Universidad Católica de Chile, Santiago, Chile.
Acta Paediatr. 2014 Sep;103(9):913-21. doi: 10.1111/apa.12689. Epub 2014 Jul 21.
Postinfectious bronchiolitis obliterans (PIBO) is an infrequent chronic lung that causes irreversible obstruction and, or, obliteration of the smaller airways. This review particularly focuses on more than 30 studies from South America.
The initial PIBO event occurs in the early years of life and is strongly associated with adenovirus infection and the need for mechanical ventilator support. Treatment requires a multidisciplinary strategy. Multicentre studies are needed to determine progression, optimal management and long-term follow-up.
感染后闭塞性细支气管炎(PIBO)是一种罕见的慢性肺部疾病,可导致小气道不可逆的阻塞和/或闭塞。本综述特别关注了来自南美洲的30多项研究。
最初的PIBO事件发生在生命早期,与腺病毒感染以及机械通气支持需求密切相关。治疗需要多学科策略。需要开展多中心研究以确定疾病进展、最佳管理方案和长期随访情况。