快速了解肥胖：体内的敌人。
A quick look at obesity; the enemy within.
作者信息
Hassanzadeh Parichehr
机构信息
Research Institute for Gastroenterology and Liver Disease, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
出版信息
Gastroenterol Hepatol Bed Bench. 2011 Fall;4(4):186-91.
Obesity with an increasing prevalence rate worldwide is correlated with multiple comorbidities. Unfortunately, the currently available therapies such as the pharmacotherapy, bariatric surgery or gene-transfer technology are associated with a number of disadvantages including undesirable side effects, poor compliance or transient effectiveness. Therefore, modifications of the lifestyle factors might be of great importance. Recently, neurotrophic factors and their metabotrophic potential in targeted pharmacology against obesity has been the focus of intense research. Meanwhile, because of the complexity and multi-factorial nature of obesity, it will still remain as a challenging medical problem.
肥胖在全球范围内的患病率不断上升，与多种合并症相关。不幸的是，目前可用的治疗方法，如药物治疗、减肥手术或基因转移技术，都存在一些缺点，包括不良副作用、依从性差或效果短暂。因此，改变生活方式因素可能非常重要。最近，神经营养因子及其在肥胖靶向药理学中的代谢营养潜力一直是深入研究的焦点。与此同时，由于肥胖的复杂性和多因素性质，它仍将是一个具有挑战性的医学问题。
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