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用于移植的大鼠胰腺保存

Rat pancreas preservation for transplantation.

作者信息

Howden B, Jablonski P, Biguzas M, Brook W, Marshall V C

机构信息

Department of Surgery, Monash University, Prince Henry's Hospital, Melbourne, Australia.

出版信息

Transplant Proc. 1987 Feb;19(1 Pt 2):1011-2.

PMID:2484091
Abstract

This study has shown that phosphate-buffered sucrose is a suitable preserving solution for the cold storage of rat pancreata for 24 hours. Isotonic citrate does not appear to be as effective a preserving solution under these conditions. Preservation of endocrine function is evident, but preservation of exocrine function is effected by obstruction or occlusion of the ductocystostomy, which may occur some time after transplantation and may not be related to transplant conditions.

摘要

本研究表明,磷酸缓冲蔗糖溶液是大鼠胰腺冷藏24小时的合适保存液。在这些条件下,等渗柠檬酸盐似乎不是一种有效的保存液。内分泌功能的保存是明显的,但外分泌功能的保存受导管囊肿造口术阻塞或闭塞的影响,这种情况可能在移植后一段时间发生,且可能与移植条件无关。

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